Department of Pathology, Universiti Sains Malaysia, Kelantan, 16150 Kubang Kerian, Malaysia.
Evid Based Complement Alternat Med. 2012;2012:410406. doi: 10.1155/2012/410406. Epub 2012 Jun 17.
Honey and cancer has a sustainable inverse relationship. Carcinogenesis is a multistep process and has multifactorial causes. Among these are low immune status, chronic infection, chronic inflammation, chronic non healing ulcers, obesity, and so forth. There is now a sizeable evidence that honey is a natural immune booster, natural anti-inflammatory agent, natural antimicrobial agent, natural cancer "vaccine," and natural promoter for healing chronic ulcers and wounds. Though honey has substances of which the most predominant is a mixture of sugars, which itself is thought to be carcinogenic, it is understandable that its beneficial effect as anticancer agent raises skeptics. The positive scientific evidence for anticancer properties of honey is growing. The mechanism on how honey has anticancer effect is an area of great interest. Among the mechanisms suggested are inhibition of cell proliferation, induction of apoptosis, and cell-cycle arrest. Honey and cancer has sustainable inverse relationship in the setting of developing nations where resources for cancer prevention and treatment are limited.
蜂蜜与癌症呈可持续的反比关系。癌症的发生是一个多步骤的过程，具有多因素的原因。其中包括免疫功能低下、慢性感染、慢性炎症、慢性非愈合性溃疡、肥胖等。现在有大量证据表明，蜂蜜是一种天然的免疫增强剂、天然的抗炎剂、天然的抗菌剂、天然的癌症“疫苗”，也是促进慢性溃疡和伤口愈合的天然物质。尽管蜂蜜含有物质，其中最主要的是糖的混合物，而这种混合物本身被认为是致癌的，但可以理解的是，它作为抗癌剂的有益效果引起了人们的怀疑。关于蜂蜜抗癌特性的积极科学证据正在不断增加。蜂蜜如何具有抗癌作用的机制是一个非常感兴趣的领域。其中提出的机制包括抑制细胞增殖、诱导细胞凋亡和细胞周期停滞。在癌症预防和治疗资源有限的发展中国家，蜂蜜与癌症呈可持续的反比关系。
