Suppr超能文献

骨肿瘤的术前经动脉栓塞术

Preoperative transarterial Embolisation in bone tumors.

作者信息

Gupta Pankaj, Gamanagatti Shivanand

机构信息

Pankaj Gupta, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

出版信息

World J Radiol. 2012 May 28;4(5):186-92. doi: 10.4329/wjr.v4.i5.186.

Abstract

Bone tumors include a variety of lesions, both primary and metastatic. The treatment modalities for bone tumors vary with the individual lesion, but in general surgical excision is the treatment of choice with other adjunctive therapies. However, surgery for many bone tumors is complex due to several factors including tumor bulk, vascularity, vicinity to vital structures and potentially inaccessible location of the lesion. Transarterial Embolisation (TAE) is one of the important adjuvant treatment modalities and in some cases it may be the primary and curative treatment. Preoperative TAE has proved to be effective in both primary and metastatic bone tumors. It reduces tumor vascularity and intraoperative blood loss, the need for blood transfusion and associated complications, allows better definition of tissue planes at surgery affording more complete excision, and hence reduced recurrence. Preoperative chemoEmbolisation has also been shown to increase the sensitivity of some tumors to subsequent chemotherapy and radiotherapy. There are several techniques and embolic agents available for this purpose, but the ultimate aim is to achieve tumor devascularization. In this review, we discuss the techniques including the choice of embolic agent, application to individual lesions and potential complications.

摘要

骨肿瘤包括多种原发性和转移性病变。骨肿瘤的治疗方式因个体病变而异,但一般来说,手术切除是主要治疗方法,并辅以其他治疗。然而,由于多种因素,包括肿瘤大小、血管分布、与重要结构的毗邻关系以及病变可能难以到达的位置,许多骨肿瘤的手术都很复杂。经动脉栓塞术(TAE)是重要的辅助治疗方式之一,在某些情况下可能是主要的根治性治疗方法。术前TAE已被证明在原发性和转移性骨肿瘤中均有效。它可减少肿瘤血管供应和术中失血、输血需求及相关并发症,使手术时组织层面更清晰,从而能更完整地切除肿瘤,进而降低复发率。术前化疗栓塞也已显示可提高某些肿瘤对后续化疗和放疗的敏感性。为此有多种技术和栓塞剂可供选择,但最终目的是实现肿瘤去血管化。在本综述中,我们将讨论相关技术,包括栓塞剂的选择、应用于个体病变以及潜在并发症。

相似文献

1
Preoperative transarterial Embolisation in bone tumors.
World J Radiol. 2012 May 28;4(5):186-92. doi: 10.4329/wjr.v4.i5.186.
2
Embolization of musculoskeletal bone tumors.
Semin Intervent Radiol. 2010 Jun;27(2):111-23. doi: 10.1055/s-0030-1253510.
3
Treatment of hepatic metastases from medullary thyroid cancer with transarterial embolisation.
Eur Radiol Exp. 2017;1(1):9. doi: 10.1186/s41747-017-0013-6. Epub 2017 Jun 29.
4
Transarterial (chemo)embolisation versus no intervention or placebo for liver metastases.
Cochrane Database Syst Rev. 2020 Mar 12;3(3):CD009498. doi: 10.1002/14651858.CD009498.pub4.
5
Preoperative transcatheter arterial embolization of hypervascular metastatic tumors of long bones.
Acta Radiol. 2010 May;51(4):396-401. doi: 10.3109/02841851003660081.
6
Preoperative embolization of primary bone tumors: A case control study.
World J Radiol. 2016 Apr 28;8(4):378-89. doi: 10.4329/wjr.v8.i4.378.
7
Overview of resistance to systemic therapy in patients with breast cancer.
Adv Exp Med Biol. 2007;608:1-22. doi: 10.1007/978-0-387-74039-3_1.
8
The role of preoperative transarterial embolization in spinal tumors. A large single-center experience.
Spine J. 2013 Feb;13(2):141-9. doi: 10.1016/j.spinee.2012.10.031. Epub 2012 Dec 6.
9
Transarterial (chemo)embolisation versus no intervention or placebo intervention for liver metastases.
Cochrane Database Syst Rev. 2013 Apr 30(4):CD009498. doi: 10.1002/14651858.CD009498.pub3.
10
Transarterial (chemo)embolisation versus no intervention or placebo intervention for liver metastases.
Cochrane Database Syst Rev. 2012 Sep 12(9):CD009498. doi: 10.1002/14651858.CD009498.pub2.

引用本文的文献

2
The Role of Preoperative Embolization in the Management of Aneurysmal Bone Cyst: A Comparative Analysis.
Indian J Orthop. 2023 May 27;57(9):1401-1408. doi: 10.1007/s43465-023-00908-4. eCollection 2023 Sep.
3
Preoperative Arterial Embolization of Musculoskeletal Tumors: A Tertiary Center Experience.
Cancers (Basel). 2023 May 8;15(9):2657. doi: 10.3390/cancers15092657.
6
Update on Preoperative Embolization of Bone Metastases.
Semin Intervent Radiol. 2019 Aug;36(3):241-248. doi: 10.1055/s-0039-1693120. Epub 2019 Aug 19.
7
Review of robotic-assisted surgery: what the future looks like through a spine oncology lens.
Ann Transl Med. 2019 May;7(10):224. doi: 10.21037/atm.2019.04.69.
8
Transarterial embolization for renal angiomyolipomas: A single centre experience in 79 patients.
J Int Med Res. 2017 Apr;45(2):706-713. doi: 10.1177/0300060516684251. Epub 2017 Jan 30.
9
Preoperative embolization of primary bone tumors: A case control study.
World J Radiol. 2016 Apr 28;8(4):378-89. doi: 10.4329/wjr.v8.i4.378.
10

本文引用的文献

1
Embolization of musculoskeletal bone tumors.
Semin Intervent Radiol. 2010 Jun;27(2):111-23. doi: 10.1055/s-0030-1253510.
2
Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate.
Skeletal Radiol. 2010 Feb;39(2):161-7. doi: 10.1007/s00256-009-0757-z.
3
Embolization of an unusual metastatic site of hepatocellular carcinoma in the humerus.
World J Gastroenterol. 2009 May 14;15(18):2280-2. doi: 10.3748/wjg.15.2280.
5
Giant cell tumor of the spine.
Neurosurg Clin N Am. 2008 Jan;19(1):49-55. doi: 10.1016/j.nec.2007.09.009.
6
Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma.
Acta Oncol. 2007;46(7):1012-8. doi: 10.1080/02841860701280725.
8
Musculoskeletal interventional radiology: applications to oncology.
Semin Roentgenol. 2007 Jul;42(3):164-74. doi: 10.1053/j.ro.2007.04.004.
9
Serial arterial embolization for large sacral giant-cell tumors: mid- to long-term results.
Spine (Phila Pa 1976). 2007 May 1;32(10):1107-15. doi: 10.1097/01.brs.0000261558.94247.8d.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验