Pediatric ENT Department, Buzzi Children's Hospital, Istituti Clinici di Perfezionamento, Via Castelvetro 32, Milan, Italy.
Pediatr Allergy Immunol. 2012 Aug;23 Suppl 22:32-44. doi: 10.1111/j.1399-3038.2012.01322.x.
: Chronic rhinosinusitis (CRS) in children is difficult to treat, with resultant frequent recurrences and failures. There are controversies in the treatment, mirroring the debate over the exact etiology of this disorder. The available medical treatments are antibiotics, topical nasal corticosteroids, and nasal lavage with saline solutions; though, there is no general agreement on the efficacy of the latter. The new technique of balloon sinuplasty allows ventilation to the sinuses to be restored with minimal risk and trauma to the tissues, and initial outcome seems promising, being successful in most treated children. Concerning the surgical approach, adenoidectomy is among the most frequent surgical procedures performed on children, but its therapeutic effect is controversial, because randomized studies have failed to prove that adenoidectomy alone is sufficient in curing CRS. Instead, functional endoscopic sinus surgery is a minimally invasive technique which restores the sinus ostia patency and can re-establish ventilation and drainage through the natural pathways. It is important that the effectiveness of any treatment is also evaluated by patient-reported outcomes (PROs) that refer to all health-related reports coming from the patients, without any involvement or interpretations by physician or others. Among PROs, health-related quality of life (HRQL) is the one most widely known and used. HRQL can be measured by means of validated questionnaires, which provide scores proportional to the degree of well-being perceived by patients. Concerning diseases of the upper airway including RS, there are numerous instruments specifically designed for children and caregivers, which allow to assess the effects of treatments in a more extensive and complete manner.
儿童慢性鼻-鼻窦炎(CRS)难以治疗,经常复发且治疗效果不佳。其治疗存在争议,这反映了对该病确切病因的争论。现有的治疗方法包括抗生素、局部鼻腔皮质类固醇和盐水鼻腔灌洗;尽管,后者的疗效尚无定论。球囊扩张鼻窦成形术这一新技术可以在最小的组织损伤和风险下恢复鼻窦通气,初步结果似乎很有前景,大多数接受治疗的儿童都取得了成功。关于手术方法,腺样体切除术是儿童最常见的手术之一,但它的治疗效果存在争议,因为随机研究未能证明腺样体切除术单独足以治愈 CRS。相反,功能性内镜鼻窦手术是一种微创技术,它可以恢复鼻窦口的通畅,并通过自然途径重新建立通气和引流。重要的是,任何治疗的有效性还可以通过患者报告的结果(PROs)来评估,这些结果涉及来自患者的所有与健康相关的报告,而无需医生或其他人的任何干预或解释。在 PROs 中,健康相关生活质量(HRQL)是最广为人知和使用的。HRQL 可以通过经过验证的问卷进行测量,这些问卷提供与患者感知的幸福感成正比的分数。对于包括 RS 在内的上呼吸道疾病,有许多专门为儿童和照顾者设计的仪器,可以更广泛和全面地评估治疗效果。