干细胞：一种散发性的超级状态。 - Suppr

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超能文献

Stem cells: a sporadic super state.

作者信息

Surani Azim, Tischler Julia

机构信息

Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.

出版信息

Nature. 2012 Jul 4;487(7405):43-5. doi: 10.1038/487043a.

DOI:10.1038/487043a

PMID:22763548

Abstract

摘要

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本文引用的文献

Embryonic stem cell potency fluctuates with endogenous retrovirus activity.胚胎干细胞的多能性随内源性逆转录病毒活性而波动。

Nature. 2012 Jul 5;487(7405):57-63. doi: 10.1038/nature11244.

Control of ground-state pluripotency by allelic regulation of Nanog.等位基因调控 Nanog 控制细胞的多能性。

Nature. 2012 Feb 12;483(7390):470-3. doi: 10.1038/nature10807.

Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.通过早期内胚层转录本的翻译扩增揭示胚胎干细胞的功能异质性。

PLoS Biol. 2010 May 25;8(5):e1000379. doi: 10.1371/journal.pbio.1000379.

Zscan4 regulates telomere elongation and genomic stability in ES cells.Zscan4 调节胚胎干细胞中端粒延伸和基因组稳定性。

Nature. 2010 Apr 8;464(7290):858-63. doi: 10.1038/nature08882. Epub 2010 Mar 24.

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.Nanog表达的规律性波动介导胚胎干细胞的细胞命运决定。

PLoS Biol. 2009 Jul;7(7):e1000149. doi: 10.1371/journal.pbio.1000149. Epub 2009 Jul 7.

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse.小鼠囊胚谱系形成、早期胚胎不对称性及轴模式形成

Development. 2009 Mar;136(5):701-13. doi: 10.1242/dev.017178.

Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states.具有不同功能和表观遗传状态的小鼠多能干细胞的动态平衡和异质性。

Cell Stem Cell. 2008 Oct 9;3(4):391-401. doi: 10.1016/j.stem.2008.07.027.

Identification and characterization of subpopulations in undifferentiated ES cell culture.未分化胚胎干细胞培养中细胞亚群的鉴定与表征

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Nanog safeguards pluripotency and mediates germline development.Nanog可维持多能性并介导种系发育。

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Retrotransposons regulate host genes in mouse oocytes and preimplantation embryos.逆转座子在小鼠卵母细胞和植入前胚胎中调控宿主基因。

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