Inserm, U1061, Montpellier, France.
PLoS One. 2012;7(6):e39879. doi: 10.1371/journal.pone.0039879. Epub 2012 Jun 29.
Resilience is the ability of individuals to adapt positively in the face of trauma. Little is known, however, about lifetime factors affecting resilience.
We assessed the effects of psychiatric disorder and lifetime trauma history on the resilience self-evaluation using the Connor-Davidson Resilience Scale (CD-RISC-10) in a high-risk-women sample. Two hundred and thirty eight community-dwelling women, including 122 participants in a study of breast cancer survivors and 116 participants without previous history of cancer completed the CD-RISC-10. Lifetime psychiatric symptoms were assessed retrospectively using two standardized psychiatric examinations (Mini International Neuropsychiatric Interview and Watson's Post-Traumatic Stress Disorder Inventory).
Multivariate logistic regression adjusted for age, education, trauma history, cancer, current psychiatric diagnoses, and psychoactive treatment indicated a negative association between current psychiatric disorder and high resilience compared to low resilience level (OR = 0.44, 95% CI [0.21-0.93]). This was related to anxiety and not mood disorder. A positive and independent association with a trauma history was also observed (OR = 3.18, 95% CI [1.44-7.01]).
Self-evaluation of resilience is influenced by both current anxiety disorder and trauma history. The independent positive association between resilience and trauma exposure may indicate a "vaccination" effect. This finding need to be taken into account in future studies evaluating resilience in general or clinical populations.
韧性是个体面对创伤时积极适应的能力。然而,人们对影响韧性的终身因素知之甚少。
我们使用 Connor-Davidson 韧性量表(CD-RISC-10)评估了精神障碍和终生创伤史对韧性自我评估的影响,该量表用于评估高风险女性样本。238 名社区居住的女性,包括 122 名乳腺癌幸存者研究参与者和 116 名无癌症既往史的参与者完成了 CD-RISC-10 量表。使用两种标准化精神科检查(Mini 国际神经精神访谈和 Watson 的创伤后应激障碍清单)回顾性评估终生精神症状。
调整年龄、教育、创伤史、癌症、当前精神诊断和精神活性治疗的多变量逻辑回归表明,与低韧性水平相比,当前精神障碍与高韧性水平呈负相关(OR=0.44,95%CI[0.21-0.93])。这与焦虑症有关,而与心境障碍无关。也观察到与创伤史呈正相关且独立的关联(OR=3.18,95%CI[1.44-7.01])。
韧性的自我评估受到当前焦虑障碍和创伤史的影响。韧性与创伤暴露之间独立的正相关可能表明存在“疫苗”效应。在评估一般或临床人群的韧性的未来研究中,需要考虑这一发现。