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橙色红色色素沉着、耐辐射的解蛋白嗜皮菌模式菌株(MRP(T))的全基因组序列

Complete genome sequence of the orange-red pigmented, radioresistant Deinococcus proteolyticus type strain (MRP(T)).

作者信息

Copeland Alex, Zeytun Ahmet, Yassawong Montri, Nolan Matt, Lucas Susan, Hammon Nancy, Deshpande Shweta, Cheng Jan-Fang, Han Cliff, Tapia Roxanne, Goodwin Lynne A, Pitluck Sam, Mavromatis Konstantinos, Liolios Konstantinos, Pagani Ioanna, Ivanova Natalia, Mikhailova Natalia, Pati Amrita, Chen Amy, Palaniappan Krishna, Land Miriam, Hauser Loren, Jeffries Cynthia D, Brambilla Evelyne-Marie, Rohde Manfred, Sikorski Johannes, Pukall Rüdiger, Göker Markus, Detter John C, Woyke Tanja, Bristow James, Eisen Jonathan A, Markowitz Victor, Hugenholtz Philip, Kyrpides Nikos C, Klenk Hans-Peter, Lapidus Alla

出版信息

Stand Genomic Sci. 2012 May 25;6(2):240-50. doi: 10.4056/sigs.2756060. Epub 2012 Apr 27.

DOI:10.4056/sigs.2756060
PMID:22768367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3387796/
Abstract

Deinococcus proteolyticus (ex Kobatake et al. 1973) Brook and Murray 1981 is one of currently 47 species in the genus Deinococcus within the family Deinococcaceae. Strain MRP(T) was isolated from feces of Lama glama and possesses extreme radiation resistance, a trait is shares with various other species of the genus Deinococcus, with D. proteolyticus being resistant up to 1.5 Mrad of gamma radiation. Strain MRP(T) is of further interest for its carotenoid pigment. The genome presented here is only the fifth completed genome sequence of a member of the genus Deinococcus (and the forth type strain) to be published, and will hopefully contribute to a better understanding of how members of this genus adapted to high gamma- or UV ionizing-radiation. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 2,886,836 bp long genome with its four large plasmids of lengths 97 kbp, 132 kbp, 196 kbp and 315 kbp harbors 2,741 protein-coding and 58 RNA genes and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

摘要

解蛋白嗜放射菌(源自小畑等,1973年)布鲁克和默里,1981年,是嗜放射菌科嗜放射菌属目前47个物种之一。菌株MRP(T)从羊驼粪便中分离得到,具有极强的抗辐射能力,该特性在嗜放射菌属的其他多种物种中也有体现,解蛋白嗜放射菌对高达1.5兆拉德的γ辐射具有抗性。菌株MRP(T)因其类胡萝卜素色素而更具研究价值。此处呈现的基因组是嗜放射菌属成员(也是第四株模式菌株)已发表的第五个完整基因组序列,有望有助于更好地理解该属成员如何适应高剂量γ或紫外线电离辐射。在此,我们描述该生物体的特征,以及完整的基因组序列和注释。这个长度为2,886,836 bp的基因组及其4个长度分别为97 kbp、132 kbp、196 kbp和315 kbp的大质粒,含有2,741个蛋白质编码基因和58个RNA基因,是细菌和古菌基因组百科全书项目的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/fadd4ef014cd/sigs.2756060-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/10f400b589f2/sigs.2756060-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/100ccdcf6b0b/sigs.2756060-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/fadd4ef014cd/sigs.2756060-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/10f400b589f2/sigs.2756060-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/100ccdcf6b0b/sigs.2756060-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/3387796/fadd4ef014cd/sigs.2756060-f3.jpg

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