Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Chin J Integr Med. 2012 Jul;18(7):543-7. doi: 10.1007/s11655-012-1142-7. Epub 2012 Jul 7.
Isobavachalcone (IBC) or (E)-1-[2,4-dihydroxy-3-(3-methyl-2-butenyl)-phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one or (E)-4,2',4'-trihydroxy-3'-prenylchalcone; 2',4,4'-trihydroxy-3'-prenyl-transchalcone, is a prenylated chalcone of the class flavonoid, firstly isolated from Psoralea corylifolia in 1968. IBC is known to possess a wide spectrum of biological activities, antibacterial, antifungal, anticancer, anti-reverse transcriptase, antitubercular and antioxidant. The compound was isolated from plant families, mostly Moraceae and Fabaceae. This review brings out together the knowledge on IBC, and can serve as the start point for future research and valorization accomplishments.
异甘草查尔酮（IBC）或（E）-1-[2,4-二羟基-3-（3-甲基-2-丁烯基）-苯基]-3-（4-羟基苯基）-2-丙烯-1-酮或（E）-4,2',4'-三羟基-3'-烯丙基查尔酮；2',4,4'-三羟基-3'-烯丙基反式查尔酮，是一种类黄酮的烯丙基查尔酮，于 1968 年首次从补骨脂中分离得到。IBC 具有广泛的生物活性，包括抗菌、抗真菌、抗癌、抗逆转录酶、抗结核和抗氧化作用。该化合物已从 Moraceae 和 Fabaceae 等植物科中分离出来。本文综述了 IBC 的相关知识，可为今后的研究和开发成果提供参考。
