Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA.
Neurosurgery. 2012 Oct;71(4):833-42. doi: 10.1227/NEU.0b013e31826772cb.
Lumbar discectomy is the most commonly performed spine procedure. Academic spine centers with potentially differing caseloads and experience may have different outcomes.
To determine whether the choice of center in which surgery is performed affects lumbar discectomy outcomes.
Spine Patient Outcomes Research Trial participants with a confirmed diagnosis of intervertebral disc herniation undergoing standard first-time open discectomy were followed from baseline at 6 weeks, and 3, 6, and 12 months, and yearly thereafter, at 13 spine clinics in 11 US states. Patient data from this prospective study were reviewed. Enrollment began in March 2000 and ended in November 2004.
Seven hundred ninety-two patients underwent first-time lumbar discectomy. Significant differences were found among centers in patient age and race, baseline levels of disability, and treatment preferences. There were no significant differences among the centers in other patient characteristics (eg, sex, body mass index, the prevalence of smoking, diabetes, or hypertension), or disease characteristics (herniation level or type). Some short-term outcomes varied significantly among centers, including operative duration and blood loss, the incidence of durotomy, the length of hospital stay, and reoperation rate. However, there were no differences among the centers in incidence of nerve root injury, postoperative mortality, Short Form 36 scores of body pain or physical function, or Oswestry Disability Index at 4 years.
Although mean blood loss, risk of durotomy, length of stay, and rate of reoperation vary among academic spine centers performing lumbar discectomy, there appears to be no difference in long-term functional outcomes.
腰椎间盘切除术是最常施行的脊柱手术。具有不同病例量和经验的学术脊柱中心可能具有不同的结果。
确定手术施行中心的选择是否会影响腰椎间盘切除术的结果。
脊柱患者结局研究试验的参与者,这些患者确诊为椎间盘突出症,行标准初次开放性椎间盘切除术,在基线时(6 周)和术后 3、6 和 12 个月以及此后每年进行随访,随访地点为美国 11 个州的 13 个脊柱诊所。对这项前瞻性研究的患者数据进行了回顾。入组始于 2000 年 3 月,结束于 2004 年 11 月。
792 例患者接受初次腰椎间盘切除术。各中心间在患者年龄和种族、基线残疾程度和治疗偏好方面存在显著差异。在其他患者特征(如性别、体重指数、吸烟、糖尿病或高血压的患病率)或疾病特征(疝出水平或类型)方面,各中心间无显著差异。一些短期结局在中心间存在显著差异,包括手术时间和失血量、硬脊膜切开术的发生率、住院时间和再次手术率。然而,各中心间神经根损伤、术后死亡率、短期 36 项健康调查简表身体疼痛或身体功能评分、Oswestry 残疾指数在 4 年时的差异无统计学意义。
尽管施行腰椎间盘切除术的学术脊柱中心间平均失血量、硬脊膜切开术风险、住院时间和再次手术率存在差异,但长期功能结局似乎并无差异。