Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Fitoterapia. 2012 Oct;83(7):1191-5. doi: 10.1016/j.fitote.2012.07.001. Epub 2012 Jul 14.
Four new chamigrane derivatives, laurecomin A (1), laurecomin B (2), laurecomin C (3), and laurecomin D (4), one new naturally occurring sesquiterpene, 2,10-dibromo-3-chloro-7-chamigren-9-ol acetate (5), and three known halogenated structures, deoxyprepacifenol (6), 1-bromoselin-4(14),11-diene (7), and 9-bromoselin-4(14),11-diene (8), were isolated from the marine red alga Laurencia composita collected from Pingtan Island, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The bioassay results showed that 2 was active against both brine shrimp and fungus Colletotrichum lagenarium.
从中国平潭岛采集的海洋红藻柳珊瑚中分离得到了 4 种新的 Chamigrane 衍生物，分别为 laurecomin A（1）、laurecomin B（2）、laurecomin C（3）和 laurecomin D（4），1 种新的天然倍半萜，2,10-二溴-3-氯-7-Chamigren-9-醇乙酸酯（5），以及 3 种已知的卤化结构，deoxyprepacifenol（6）、1-溴selin-4(14),11-二烯（7）和 9-溴selin-4(14),11-二烯（8）。这些化合物的结构通过 1D、2D NMR 和质谱技术得到了明确的确定。生物测定结果表明，化合物 2 对卤虫和真菌胶孢炭疽菌均具有活性。
