2型轮状病毒引起的胃肠炎常见暴露性暴发，家庭内二代发病率高。

Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families.

作者信息

Rodriguez W J, Kim H W, Brandt C D, Yolken R H, Richard M, Arrobio J O, Schwartz R H, Kapikian A Z, Chanock R M, Parrott R H

出版信息

J Infect Dis. 1979 Sep;140(3):353-7. doi: 10.1093/infdis/140.3.353.

DOI:10.1093/infdis/140.3.353

PMID:227970

Abstract

A sharp outbreak of gastroenteritis associated with human rotavirus type 2 involved not only all of nine infants and young children in a playgroup but also seven of 10 parents and grandparents studied. The source of the outbreak appeared to be two non-playgroup siblings. Six of 11 individuals studied shed human rotavirus type 2, and each of seven from whom paired sera were obtained developed a type 2 sero-response. Overall, evidence of infection with rotavirus type 2 was demonstrated in 10 of 11 individuals by detection of virus in stools and/or a serologic response in an enzyme-linked immunosorbent assay.

摘要

一场与2型人类轮状病毒相关的急性肠胃炎暴发，不仅涉及一个幼儿游戏小组中的所有9名婴幼儿，还涉及所研究的10名父母及祖父母中的7人。此次暴发的源头似乎是两个非游戏小组的兄弟姐妹。在所研究的11个人中，有6人排出2型人类轮状病毒，在采集了配对血清的7人中，每个人都产生了2型血清反应。总体而言，通过检测粪便中的病毒和/或酶联免疫吸附测定中的血清学反应，在11个人中的10人身上证实了感染2型轮状病毒的证据。