Stout N, Partsch H, Szolnoky G, Forner-Cordero I, Mosti G, Mortimer P, Flour M, Damstra R, Piller N, Geyer M J, Benigni J-P, Moffat C, Cornu-Thenard A, Schingale F, Clark M, Chauveau M
Breast Care Department, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Int Angiol. 2012 Aug;31(4):316-29.
Chronic edema is a multifactorial condition affecting patients with various diseases. Although the pathophysiology of edema varies, compression therapy is a basic tenant of treatment, vital to reducing swelling. Clinical trials are disparate or lacking regarding specific protocols and application recommendations for compression materials and methodology to enable optimal efficacy. Compression therapy is a basic treatment modality for chronic leg edema; however, the evidence base for the optimal application, duration and intensity of compression therapy is lacking. The aim of this document was to present the proceedings of a day-long international expert consensus group meeting that examined the current state of the science for the use of compression therapy in chronic edema. An expert consensus group met in Brighton, UK, in March 2010 to examine the current state of the science for compression therapy in chronic edema of the lower extremities. Panel discussions and open space discussions examined the current literature, clinical practice patterns, common materials and emerging technologies for the management of chronic edema. This document outlines a proposed clinical research agenda focusing on compression therapy in chronic edema. Future trials comparing different compression devices, materials, pressures and parameters for application are needed to enhance the evidence base for optimal chronic oedema management. Important outcomes measures and methods of pressure and oedema quantification are outlined. Future trials are encouraged to optimize compression therapy in chronic edema of the lower extremities.
慢性水肿是一种影响多种疾病患者的多因素病症。尽管水肿的病理生理学各不相同，但压迫疗法是治疗的一项基本原则，对于减轻肿胀至关重要。关于压迫材料和方法的具体方案及应用建议，临床试验存在差异或缺乏相关研究，以实现最佳疗效。压迫疗法是慢性腿部水肿的一种基本治疗方式；然而，缺乏关于压迫疗法最佳应用、持续时间和强度的循证依据。本文档的目的是介绍一次为期一天的国际专家共识小组会议的会议记录，该会议审查了慢性水肿中使用压迫疗法的科学现状。一个专家共识小组于2010年3月在英国布莱顿召开会议，审查下肢慢性水肿中压迫疗法的科学现状。小组讨论和开放式讨论审查了慢性水肿管理的当前文献、临床实践模式、常用材料和新兴技术。本文档概述了一项拟议的临床研究议程，重点是慢性水肿中的压迫疗法。需要未来的试验来比较不同的压迫装置、材料、压力和应用参数，以加强最佳慢性水肿管理的循证依据。文中概述了重要的结局指标以及压力和水肿量化方法。鼓励未来的试验优化下肢慢性水肿的压迫疗法。
