Jefferies John L, Morales David L
The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2003, Cincinnati, OH 45229, USA.
Curr Heart Fail Rep. 2012 Sep;9(3):236-43. doi: 10.1007/s11897-012-0103-y.
The number of children and adolescents suffering from heart failure is increasing dramatically. Some of these patients will progress to need advanced therapies in the form of mechanical circulatory support (MCS). Over the past few years, increased attention has been focused on clinical use of existing devices as well the development of pediatric-specific ventricular assist devices (VADs). As in adult populations, these devices offer unique opportunities to successfully support children as a bridge-to-transplant, but increasing data suggest that bridge-to-recovery and bridge-to-destination are also viable options in select pediatric populations. Herein, we will review existing approaches as well describe future potential MCS options.
患有心力衰竭的儿童和青少年数量正在急剧增加。其中一些患者将逐渐需要以机械循环支持(MCS)形式的先进疗法。在过去几年中,人们越来越关注现有设备的临床应用以及儿科专用心室辅助设备(VAD)的开发。与成人患者一样,这些设备为成功支持儿童作为移植桥梁提供了独特的机会,但越来越多的数据表明,在特定的儿科人群中,过渡到康复和过渡到终点也是可行的选择。在此,我们将回顾现有方法并描述未来潜在的MCS选项。