Afshar A Aghaei, Rassi Y, Sharifi I, Abai Mr, Oshaghi Ma, Yaghoobi-Ershadi Mr, Vatandoost H
Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Iran.
Iran J Arthropod Borne Dis. 2011;5(2):32-41. Epub 2011 Dec 31.
The cutaneous leishmaniasis (CL) has been occurred in Dehbakri County, located 46 km of Bam District, Kerman Province since 2004-2005. Phlebotomus papatasi is an important vector of zoonotic cutaneous leishmanisis (ZCL) as well as sand fly fever and P. sergenti is considered as main vector of anthroponotic cutaneous leishmaniasis (ACL) in Iran. There are several measures for vector control with emphasizing on insecticides. The objective of this study was to determine the baseline susceptibility of leishmaniasis vectors to the DDT and deltamethrin in an endemic focus of CL in southern Iran.
Baseline susceptibility tests were carried out on field collected strains of P. papatasi and P. sergenti and tested with WHO impregnated papers with DDT 4.0% and deltamethrin 0.05% in the focus of disease in Dehbakri County during summer 2010. The values of LT(50) and LT(90) were determined using probit analysis and regression lines.
The LT(50) value of DDT 4.0% and deltamethrin 0.05% against P. papatasi was 20.6 and 13.6 minutes respectively. The same data for P. sergenti were ranged between 21.8 and 17.7 minutes.
The results of tests will provide a guideline for implementation of vector control using pesticides such as impregnated bed nets, indoor residual spraying and fogging.
自2004 - 2005年以来，皮肤利什曼病（CL）在克尔曼省巴姆区46公里外的德哈卜里县出现。巴氏白蛉是动物源性皮肤利什曼病（ZCL）以及白蛉热的重要传播媒介，而伊朗的塞尔吉白蛉被认为是人间皮肤利什曼病（ACL）的主要传播媒介。有多种控制传播媒介的措施，其中重点是使用杀虫剂。本研究的目的是确定伊朗南部一个CL流行区利什曼病传播媒介对滴滴涕和溴氰菊酯的基线敏感性。
2010年夏季，在德哈卜里县疾病流行区对野外采集的巴氏白蛉和塞尔吉白蛉菌株进行了基线敏感性测试，并用含4.0%滴滴涕和0.05%溴氰菊酯的世卫组织浸渍纸进行测试。使用概率分析和回归线确定LT(50)和LT(90)值。
4.0%滴滴涕和0.05%溴氰菊酯对巴氏白蛉的LT(50)值分别为20.6分钟和13.6分钟。塞尔吉白蛉的相同数据在21.8分钟至17.7分钟之间。
测试结果将为使用浸渍蚊帐、室内滞留喷洒和喷雾等杀虫剂实施病媒控制提供指导。
