Matsuoka Masato, Ogata Nahoko, Matsuyama Kayako, Yoshikawa Tadanobu, Takahashi Kanji
Department of Ophthalmology, Kansai Medical University, Takii Hospital, Osaka.
Clin Ophthalmol. 2012;6:1005-9. doi: 10.2147/OPTH.S33131. Epub 2012 Jul 2.
To determine whether the intraocular pressure (IOP) in diabetic patients is significantly different from that in nondiabetic patients.
The medical records of all patients who were initially examined in the Department of Ophthalmology, Kansai Medical University, Takii Hospital were reviewed. At the initial examination, patients had a detailed interview and underwent a comprehensive ophthalmic examinations. All patients were over 20 years of age and did not have glaucoma.
A total of 703 patients were evaluated. The mean (±standard error) IOP of the diabetic patients was 15.5 ± 0.2 mmHg (n = 206), and was significantly higher than the 14.0 ± 0.1 mmHg (n = 497) in the nondiabetic patients (P < 0.0001). The IOP was negatively correlated with age (r = -0.202; P = 0.024) in the diabetic patients and was weakly but significantly correlated with the glycosylated hemoglobin (HbA(1c)) level (r = 0.240; P = 0.015) in the group with diabetic retinopathy.
The significantly higher IOP in diabetic patients and positive correlation of IOP with HbA(1c) levels in patients with diabetic retinopathy indicate that IOP in diabetic patients is higher, especially in those with poor control of diabetes.
确定糖尿病患者的眼压是否与非糖尿病患者存在显著差异。
回顾了在关西医科大学泷井医院眼科初诊的所有患者的病历。初诊时，患者接受了详细的问诊并进行了全面的眼科检查。所有患者年龄均超过20岁且无青光眼。
共评估了703例患者。糖尿病患者的平均（±标准误）眼压为15.5±0.2 mmHg（n = 206），显著高于非糖尿病患者的14.0±0.1 mmHg（n = 497）（P < 0.0001）。糖尿病患者的眼压与年龄呈负相关（r = -0.202；P = 0.024），在糖尿病视网膜病变组中，眼压与糖化血红蛋白（HbA(1c)）水平呈弱但显著的正相关（r = 0.240；P = 0.015）。
糖尿病患者眼压显著升高以及糖尿病视网膜病变患者眼压与HbA(1c)水平呈正相关，表明糖尿病患者的眼压较高，尤其是糖尿病控制不佳的患者。
