Comprehensive Cancer Centre South, Eindhoven, The Netherlands.
Psychooncology. 2013 Jun;22(6):1258-65. doi: 10.1002/pon.3131. Epub 2012 Jul 26.
To understand cultural differences in the impact of cancer (IOC) by (i) performing an independent psychometric evaluation of the Dutch version of the Impact of Cancer Scale version 2 (IOCv2) in a non-Hodgkin lymphoma (NHL) sample and (ii) examining differences between Dutch and American NHL survivors in perceived IOC and identifying associations with socio-demographic and clinical characteristics.
Data collected from 491 Dutch and 738 American NHL survivors were used in this study. IOCv2 responses were obtained from all survivors; the Dutch survivors also completed the European Organization for Research and Treatment of Cancer Quality of Life Core questionnaire, which measures quality of life.
Exploratory factor analysis of the Dutch version yielded a factor solution similar to the American structure but with some subscales merging into single factors. Internal consistency was good; Cronbach's alpha was 0.88 for the Positive and 0.94 for the Negative summary scales. Large differences were observed between survivors, whereby Dutch survivors reported fewer Positive (Δ -0.4, p < 0.001, effect size: 0.27) and more Negative (Δ 0.2, p ≤ 0.001, effect size: 0.13) impacts of cancer independent of socio-demographic and clinical characteristics.
Similar impact domains of the IOCv2 were observed in the Dutch sample, providing evidence that IOCv2 scales measure common and important survivor concerns across two different Western nations. Higher positive impacts for US survivors might be explained by more personal control and availability of supportive services. Future research should focus on determinants of the IOC in both Dutch and American survivors to gain better understanding of the factors that might improve it and suggest how health care may be modified toward that end.
通过（i）在非霍奇金淋巴瘤（NHL）样本中对荷兰语版癌症影响量表 2 版（IOCv2）进行独立的心理计量评估，以及（ii）检查荷兰和美国 NHL 幸存者在感知癌症影响方面的差异，并确定与社会人口统计学和临床特征的关联，了解癌症影响的文化差异。
本研究使用了来自 491 名荷兰和 738 名美国 NHL 幸存者的数据。所有幸存者都获得了 IOCv2 的反应；荷兰幸存者还完成了欧洲癌症研究与治疗组织生活质量核心问卷，该问卷用于衡量生活质量。
荷兰语版的探索性因素分析得出的因子解决方案与美国结构相似，但有些子量表合并为单个因子。内部一致性良好；阳性和阴性综合量表的 Cronbach's alpha 分别为 0.88 和 0.94。幸存者之间存在很大差异，荷兰幸存者报告的癌症阳性影响较小（Δ-0.4，p<0.001，效应大小：0.27），而负面影响较大（Δ0.2，p≤0.001，效应大小：0.13），独立于社会人口统计学和临床特征。
在荷兰样本中观察到 IOCv2 的相似影响领域，这表明 IOCv2 量表在两个不同的西方国家测量了共同且重要的幸存者关注点。美国幸存者的阳性影响较高可能是由于个人控制和支持性服务的可用性较高。未来的研究应集中于荷兰和美国幸存者的 IOC 决定因素，以更好地了解可能改善其的因素，并提出如何为此目的修改医疗保健。
