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The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.

作者信息

Dilger J P, McLaughlin S G, McIntosh T J, Simon S A

出版信息

Science. 1979 Dec 7;206(4423):1196-8. doi: 10.1126/science.228394.

DOI:10.1126/science.228394
PMID:228394
Abstract

The Born charging equation predicts that the permeability of a phospholipid bilayer membrane to ions should depend markedly on the dielectric constant of the membrane. Increasing the dielectric constant of an artificial bilayer increases its permeability to perchlorate or thiocyanate by a factor of 1000, to a value comparable to that of mitochondrial membranes.

摘要

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