Division of Research, Kaiser Foundation Research Institute, Kaiser Permanente, 2000 Broadway, Oakland, California 94612, USA.
Sci Rep. 2012;2:540. doi: 10.1038/srep00540. Epub 2012 Jul 27.
We conducted a prospective study to examine whether in-utero exposure to magnetic fields (MFs) increases the risk of childhood obesity. Participating women carried a meter measuring MF levels during pregnancy and 733 of their children were followed up to 13 years to collect clinically recorded information on growth patterns with 33 weight measurements per child on average. Prenatal exposure to high MF level was associated with increased risk of being obese in offspring than those with lower MF level (odds ratio = 1.69, 95% confidence interval: 1.01-2.84). The association demonstrated a dose-response relationship and was stronger (more than 2.3 fold increased risk) among children who were followed up to the end of the study. The association existed only for persistent obesity, but not for transitory (unlikely) obesity. Maternal exposure to high MF during pregnancy may be a new and previously unknown factor contributing to the world-wide epidemic of childhood obesity/overweight.
我们进行了一项前瞻性研究,以检验子宫内暴露于磁场(MFs)是否会增加儿童肥胖的风险。参与的女性在怀孕期间携带了一个测量 MF 水平的仪器,其中 733 名儿童被随访至 13 年,以收集平均每个孩子 33 次体重测量的临床记录的生长模式信息。与低 MF 水平相比,产前暴露于高 MF 水平与后代肥胖的风险增加相关(比值比=1.69,95%置信区间:1.01-2.84)。这种关联表现出剂量-反应关系,在随访至研究结束的儿童中更为强烈(风险增加超过 2.3 倍)。这种关联仅存在于持续性肥胖,而不存在于短暂性(不太可能)肥胖。母亲在怀孕期间暴露于高磁场可能是导致全球儿童肥胖/超重流行的一个新的、以前未知的因素。