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由产生氨基糖苷(3)-5-乙酰转移酶的耐庆大霉素革兰氏阴性杆菌引起的内源性定植。

Endogenous colonization by gentamicin-resistant gram-negative bacilli elaborating aminoglycoside (3)-5-acetyltransferase.

作者信息

Barg N L, Cooper J F

机构信息

Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.

出版信息

Antimicrob Agents Chemother. 1990 Sep;34(9):1827-9. doi: 10.1128/AAC.34.9.1827.

Abstract

Members of the family Enterobacteriaceae that elaborate aminoglycoside 3-5-acetyltransferase [AAC(3)-5] caused a nosocomial outbreak at the Vanderbilt University Medical Center and have persisted. To see whether the gene for AAC(3)-5 was present in the community, stool cultures of newly admitted patients and ambulatory persons were examined with a specific gene probe. AAC(3)-5-positive strains were present in the intestinal flora examined.

摘要

能产生氨基糖苷3 - 5 -乙酰转移酶【AAC(3)-5】的肠杆菌科细菌在范德比尔特大学医学中心引发了一次院内感染暴发,并且这类细菌一直存在。为了解社区中是否存在AAC(3)-5基因,我们用一种特异性基因探针检测了新入院患者和门诊患者的粪便培养物。在所检测的肠道菌群中存在AAC(3)-5阳性菌株。

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Review of epidemic aminoglycoside resistance worldwide.全球流行性氨基糖苷类耐药性综述。
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Characteristics of gentamicin resistance in nosocomial infections.医院感染中庆大霉素耐药的特征
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本文引用的文献

8
Persistence of an aminoglycoside-resistance determinant at a university hospital for 12 years.
J Infect Dis. 1987 Mar;155(3):586-9. doi: 10.1093/infdis/155.3.586.

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