Cardiovascular Prevention and Rehabilitation Centre (ÉPIC), Montreal Heart Institute, Montreal, Quebec, Canada.
Am J Phys Med Rehabil. 2012 Nov;91(11):941-50. doi: 10.1097/PHM.0b013e3182643ce0.
The aim of this study was to study the impact of a combined long-term lifestyle and high-intensity interval training intervention on body composition, cardiometabolic risk, and exercise tolerance in overweight and obese subjects.
Sixty-two overweight and obese subjects (53.3 ± 9.7 yrs; mean body mass index, 35.8 ± 5 kg/m(2)) were retrospectively identified at their entry into a 9-mo program consisting of individualized nutritional counselling, optimized high-intensity interval exercise, and resistance training two to three times a week. Anthropometric measurements, cardiometabolic risk factors, and exercise tolerance were measured at baseline and program completion.
Adherence rate was 97%, and no adverse events occurred with high-intensity interval exercise training. Exercise training was associated with a weekly energy expenditure of 1582 ± 284 kcal. Clinically and statistically significant improvements were observed for body mass (-5.3 ± 5.2 kg), body mass index (-1.9 ± 1.9 kg/m(2)), waist circumference (-5.8 ± 5.4 cm), and maximal exercise capacity (+1.26 ± 0.84 metabolic equivalents) (P < 0.0001 for all parameters). Total fat mass and trunk fat mass, lipid profile, and triglyceride/high-density lipoprotein ratio were also significantly improved (P < 0.0001). At program completion, the prevalence of metabolic syndrome was reduced by 32.5% (P < 0.05). Independent predictors of being a responder to body mass and waist circumference loss were baseline body mass index and resting metabolic rate; those for body mass index decrease were baseline waist circumference and triglyceride/high-density lipoprotein cholesterol ratio.
A long-term lifestyle intervention with optimized high-intensity interval exercise improves body composition, cardiometabolic risk, and exercise tolerance in obese subjects. This intervention seems safe, efficient, and well tolerated and could improve adherence to exercise training in this population.
本研究旨在探讨长期生活方式干预联合高强度间歇训练对超重和肥胖者的身体成分、心血管代谢风险和运动耐力的影响。
62 名超重和肥胖者（53.3±9.7 岁；平均体重指数 35.8±5kg/m²）在参加 9 个月的计划时被回顾性识别，该计划包括个性化营养咨询、优化的高强度间歇运动和每周两到三次的阻力训练。在基线和计划完成时测量了人体测量学测量值、心血管代谢风险因素和运动耐力。
高强度间歇运动训练的依从率为 97%，没有发生不良事件。运动训练与每周 1582±284 千卡的能量消耗有关。身体质量（-5.3±5.2kg）、体重指数（-1.9±1.9kg/m²）、腰围（-5.8±5.4cm）和最大运动能力（+1.26±0.84代谢当量）均有临床和统计学显著改善（所有参数 P<0.0001）。总脂肪量和躯干脂肪量、血脂谱和甘油三酯/高密度脂蛋白比值也显著改善（P<0.0001）。在计划完成时，代谢综合征的患病率降低了 32.5%（P<0.05）。体重和腰围减少的反应者的独立预测因子是基线体重指数和静息代谢率；体重指数下降的预测因子是基线腰围和甘油三酯/高密度脂蛋白胆固醇比值。
优化的高强度间歇运动的长期生活方式干预可改善肥胖者的身体成分、心血管代谢风险和运动耐力。这种干预似乎安全、有效且耐受良好，并可提高该人群对运动训练的依从性。
