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加拿大氡诱发肺癌的人群风险:基于近期全加拿大氡调查的重新评估。

Canadian population risk of radon induced lung cancer: a re-assessment based on the recent cross-Canada radon survey.

作者信息

Chen J, Moir D, Whyte J

机构信息

Radiation Protection Bureau, Health Canada, 2720 Riverside Drive, Ottawa, Canada K1A 0K9.

出版信息

Radiat Prot Dosimetry. 2012 Nov;152(1-3):9-13. doi: 10.1093/rpd/ncs147. Epub 2012 Aug 8.

DOI:10.1093/rpd/ncs147
PMID:22874897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3509926/
Abstract

Exposure to indoor radon has been determined to be the second leading cause of lung cancer after tobacco smoking. Canadian population risk of radon induced lung cancer was assessed in 2005 with the radon distribution characteristics determined from a radon survey carried out in the late 1970s in 19 cities. In that survey, a grab sampling method was used to measure radon levels. The observed radon concentration in 14,000 Canadian homes surveyed followed a log-normal distribution with a geometric mean (GM) of 11.2 Bq m(-3) and a geometric standard deviation (GSD) of 3.9. Based on the information from that survey, it was estimated that ∼10 % of lung cancers in Canada resulted from indoor radon exposure. To gain a better understanding of radon concentrations in homes across the country, a national residential radon survey was launched in April 2009. In the recent survey, long-term (3 month or longer) indoor radon measurements were made in roughly 14 000 homes in 121 health regions across Canada. The observed radon concentrations follow, as expected, a log-normal distribution with a GM of 41.9 Bq m(-3) and a GSD of 2.8. Based on the more accurate radon distribution characteristics obtained from the recent cross-Canada radon survey, a re-assessment of Canadian population risk for radon induced lung cancer was undertaken. The theoretical estimates show that 16 % of lung cancer deaths among Canadians are attributable to indoor radon exposure. These results strongly suggest the ongoing need for the Canadian National Radon Program. In particular, there is a need for a focus on education and awareness by all levels of government, and in partnership with key stakeholders, to encourage Canadians to take action to reduce the risk from indoor radon exposure.

摘要

室内氡暴露已被确定为仅次于吸烟的第二大肺癌致病因素。2005年,根据20世纪70年代末在19个城市进行的氡调查所确定的氡分布特征,对加拿大人群氡致肺癌风险进行了评估。在那次调查中,采用了抓取采样法来测量氡水平。在接受调查的14,000个加拿大家庭中,观测到的氡浓度呈对数正态分布,几何均值(GM)为11.2 Bq m(-3),几何标准差(GSD)为3.9。根据那次调查的信息,估计加拿大约10%的肺癌是由室内氡暴露所致。为了更好地了解全国范围内家庭中的氡浓度,2009年4月启动了一项全国性住宅氡调查。在最近的调查中,对加拿大121个卫生区域内约14,000个家庭进行了长期(3个月或更长时间)的室内氡测量。正如预期的那样,观测到的氡浓度呈对数正态分布,GM为41.9 Bq m(-3),GSD为2.8。基于最近加拿大氡调查获得的更准确的氡分布特征,对加拿大人群氡致肺癌风险进行了重新评估。理论估计表明,加拿大16%的肺癌死亡可归因于室内氡暴露。这些结果有力地表明,加拿大国家氡计划仍有持续的必要性。特别是,各级政府需要与主要利益相关者合作,专注于教育和提高认识,以鼓励加拿大人采取行动降低室内氡暴露风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6943/3509926/a304144a8fd2/ncs14701.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6943/3509926/a304144a8fd2/ncs14701.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6943/3509926/a304144a8fd2/ncs14701.jpg

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