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可配置的 3D 打印毫流控和微流控“芯片实验室”反应器件。

Configurable 3D-Printed millifluidic and microfluidic 'lab on a chip' reactionware devices.

机构信息

School of Chemistry, University of Glasgow, G12 8QQ, United Kingdom.

出版信息

Lab Chip. 2012 Sep 21;12(18):3267-71. doi: 10.1039/c2lc40761b. Epub 2012 Aug 9.

DOI:10.1039/c2lc40761b
PMID:22875258
Abstract

We utilise 3D design and 3D printing techniques to fabricate a number of miniaturised fluidic 'reactionware' devices for chemical syntheses in just a few hours, using inexpensive materials producing reliable and robust reactors. Both two and three inlet reactors could be assembled, as well as one-inlet devices with reactant 'silos' allowing the introduction of reactants during the fabrication process of the device. To demonstrate the utility and versatility of these devices organic (reductive amination and alkylation reactions), inorganic (large polyoxometalate synthesis) and materials (gold nanoparticle synthesis) processes were efficiently carried out in the printed devices.

摘要

我们利用 3D 设计和 3D 打印技术,在短短几个小时内使用廉价材料制造出许多微型流体“反应器件”,用于化学合成,这些反应器件可靠且坚固。我们可以组装两个和三个入口的反应器,也可以组装带有反应物“料斗”的单入口装置,这样可以在设备制造过程中引入反应物。为了展示这些设备的实用性和多功能性,我们在打印设备中高效地进行了有机(还原胺化和烷基化反应)、无机(多金属氧酸盐的大规模合成)和材料(金纳米粒子合成)等过程。

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