Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Chin Med J (Engl). 2012 Jul;125(14):2610-7.
To discuss the present status and progress of clinical research on the cognitive effects caused by different types of brain tumors and common treatments.
The data used in this review were mainly from PubMed articles published in English from 1990 to Febuary 2012. Research terms were "cognitive deficits" or "cognitive dysfunction".
Articals including any information about brain tumor related cognitive deficits were selected.
It is widely accepted that brain tumors and related treatments can impair cognitive function across many domains, and can impact on patients' quality of life. Tumor localization, lateralization, surgery, drugs, radiotherapy and chemotherapy are all thought to be important factors in this process. However, some conflicting findings regarding brain tumor-related cognitive deficits have been reported. It can be difficult to determine the mechanism of these treatments, such as chemotherapy, antibiotics, antiepileptics, and steroids. Future research is needed to clarify these potential treatment effects.
Cognitive function is important for patients with brain tumor. Much more focus has been paid on this field. It should be regarded as an important prognostic index for the patients with brain tumor, and neuropsychological tests should be used in regular examinations.
讨论不同类型脑肿瘤和常见治疗方法引起的认知影响的研究现状和进展。
本综述使用的数据主要来自于 1990 年至 2012 年 2 月期间发表在英文期刊 PubMed 上的文章。研究术语为“认知缺陷”或“认知功能障碍”。
选择了包含任何关于脑肿瘤相关认知缺陷信息的文章。
人们普遍认为脑肿瘤和相关治疗会损害许多领域的认知功能，并会影响患者的生活质量。肿瘤定位、偏侧化、手术、药物、放疗和化疗都被认为是这个过程中的重要因素。然而，也有一些关于脑肿瘤相关认知缺陷的相互矛盾的发现。确定这些治疗方法（如化疗、抗生素、抗癫痫药和类固醇）的机制可能具有挑战性。未来的研究需要阐明这些潜在的治疗效果。
认知功能对脑肿瘤患者很重要。人们更加关注这一领域。它应该被视为脑肿瘤患者的一个重要预后指标，应该在常规检查中使用神经心理学测试。
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