Materials Science and Engineering Program, Texas Materials Institute, Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
Adv Mater. 2012 Oct 23;24(40):5457-63. doi: 10.1002/adma.201201820. Epub 2012 Aug 9.
Surface enhanced Raman scattering (SERS) is sensitive enough for single-molecule biochemical detection, but it is extremely difficult to obtain a large number of SERS hotspots for sensitive and reproducible detection. It is even more challenging to assemble the hotspots at designated positions for location predictable sensing. Here, we report an original strategy for the synthesis, manipulation, and assembling of plasmonic nanocapsule SERS sensors for high-sensitivity biochemical detection at predictable locations.
表面增强拉曼散射（SERS）对于单分子生化检测足够灵敏，但要获得大量 SERS 热点以实现灵敏且可重现的检测非常困难。对于在指定位置组装热点以进行位置可预测传感，这就更具挑战性。在这里，我们报告了一种用于合成、操纵和组装等离子体纳米胶囊 SERS 传感器的原始策略，用于在可预测的位置进行高灵敏度的生化检测。
