State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
Planta Med. 2012 Oct;78(15):1702-5. doi: 10.1055/s-0032-1315209. Epub 2012 Aug 13.
Two new sulfur-containing triterpenoid saponins, asprellanosides A (1) and B (2), were isolated from the roots of Ilex asprella, together with 10 known compounds (3-12). An in vitro anti-HSV-1 activity test of the isolates (1-4, 6-7, and 9-12) showed that only asprellanoside A (1) and oblonganoside H (6) exhibited anti-HSV-1 activity with TIC values of 0.14 and 0.18 mM, respectively.
从苦丁茶的根部分离得到了两个新的含硫三萜皂苷，分别为 asprellanoside A（1）和 B（2），此外还分离得到了 10 个已知化合物（3-12）。对分离得到的化合物（1-4、6-7 和 9-12）进行体外抗 HSV-1 活性测试，结果表明只有 asprellanoside A（1）和 oblonganoside H（6）具有抗 HSV-1 活性，其 TIC 值分别为 0.14 和 0.18mM。
