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Sci Prog. 2012;95(Pt 2):175-98. doi: 10.3184/003685012X13361524970266.
The field of microfluidics, often also referred to as "Lab-on-a-Chip" has made significant progress in the last 15 years and is an essential tool in the development of new products and protocols in the life sciences. This article provides a broad overview on the developments on the academic as well as the commercial side. Fabrication technologies for polymer-based devices are presented and a strategy for the development of complex integrated devices is discussed, together with an example on the use of these devices in pathogen detection.
微流控领域,也常被称为“芯片实验室”,在过去的 15 年中取得了重大进展,是生命科学领域新产品和新方案开发的重要工具。本文从学术和商业两个方面对该领域的发展进行了综述。介绍了基于聚合物的器件的制造技术,并讨论了开发复杂集成器件的策略,以及这些器件在病原体检测中的应用实例。