Institute of Environmental Science and Research Limited, Christchurch, New Zealand.
Epidemiol Infect. 2013 Jun;141(6):1253-66. doi: 10.1017/S0950268812001719. Epub 2012 Aug 21.
Pulsed-field gel electrophoresis genotypes of Campylobacter isolates from 603 human patients were compared with 485 isolates from retail offal (primarily chicken and lamb) to identify temporal clusters and possible sources of campylobacteriosis. Detailed epidemiological information was collected from 364 of the patients, and when combined with genotyping data allowed a putative transmission pathway of campylobacteriosis to be assigned for 88% of patients. The sources of infection were 47% food, 28% direct animal contact, 7% overseas travel, 4% person-to-person transmission and 3% water-related. A significant summer increase in campylobacteriosis cases was primarily attributed to an increase in food-related cases. Genotyping of isolates was essential for identifying the likely cause of infection for individuals. However, a more rapid and cheaper typing tool for Campylobacter is needed, which if applied to human and animal isolates on a routine basis could advance greatly our understanding of the ongoing problem of Campylobacter infection in New Zealand.
对 603 名人类患者和 485 名零售内脏（主要是鸡肉和羊肉）中分离出的弯曲杆菌分离株的脉冲场凝胶电泳基因型进行了比较，以确定时间聚类和可能的弯曲杆菌病来源。对 364 名患者中的详细流行病学信息进行了收集，并结合基因分型数据，为 88%的患者确定了弯曲杆菌病的可能传播途径。感染源为 47%的食物、28%的直接动物接触、7%的海外旅行、4%的人际传播和 3%的与水有关。弯曲杆菌病病例在夏季的显著增加主要归因于与食物有关的病例增加。分离株的基因分型对于确定个体感染的可能原因至关重要。然而，需要一种更快、更便宜的弯曲杆菌分型工具，如果将其常规应用于人类和动物分离株，将极大地提高我们对新西兰持续存在的弯曲杆菌感染问题的理解。
