尼古丁替代疗法：患者安全性与持续性
Nicotine replacement therapies: patient safety and persistence.
作者信息
Ferguson Stuart G, Shiffman Saul, Gitchell Joseph G
机构信息
School of Pharmacy.
出版信息
Patient Relat Outcome Meas. 2011 Jul;2:111-7. doi: 10.2147/PROM.S11545. Epub 2011 Jun 14.
Abstract
Nicotine replacement therapy (NRT) has become a central part of the treatment of nicotine dependence. However, NRT's potential efficacy is limited to some extent by patient adherence and persistence. Here we review the relationship between NRT compliance and adherence, and overall treatment outcome. We then examine the factors that likely impact on treatment compliance and persistence, with a special focus on users' perceptions of treatment safety and efficacy as possible mediators. Potential clinical strategies for improving suboptimal medication use are also discussed.
摘要
尼古丁替代疗法（NRT）已成为治疗尼古丁依赖的核心组成部分。然而，NRT的潜在疗效在一定程度上受到患者依从性和持续性的限制。在此，我们回顾NRT的顺应性与依从性之间的关系以及总体治疗结果。然后，我们考察可能影响治疗顺应性和持续性的因素，特别关注使用者对治疗安全性和疗效的认知作为可能的调节因素。还讨论了改善用药欠佳情况的潜在临床策略。
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