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利用正电子发射断层扫描研究右侧颞叶的进行性退化。

Progressive degeneration of the right temporal lobe studied with positron emission tomography.

作者信息

Tyrrell P J, Warrington E K, Frackowiak R S, Rossor M N

机构信息

Medical Research Council Cyclotron Unit, Hammersmith Hospital, London, United Kingdom.

出版信息

J Neurol Neurosurg Psychiatry. 1990 Dec;53(12):1046-50. doi: 10.1136/jnnp.53.12.1046.

DOI:10.1136/jnnp.53.12.1046
PMID:2292695
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC488312/
Abstract

A 79 year old man with a twelve year progressive history of prosopagnosia and recent naming difficulty, in whom other intellectual skills were preserved, is described. Positron emission tomography (PET) revealed an area of right temporal lobe hypometabolism, with an additional area of less severe hypometabolism at the left temporal pole. This may represent an example of progressive focal cortical degeneration similar to that associated with primary progressive dysphasia, but affecting the right temporal lobe.

摘要

本文描述了一位79岁男性,他有12年进行性面孔失认症病史且近期出现命名困难,但其其他智力技能保持完好。正电子发射断层扫描(PET)显示右侧颞叶存在低代谢区域,左侧颞极还有一个不太严重的低代谢区域。这可能是一种进行性局灶性皮质变性的实例,类似于与原发性进行性失语症相关的情况,但影响的是右侧颞叶。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/77f071a42ccf/jnnpsyc00522-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/9ff6a3fe5fe1/jnnpsyc00522-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/ce9d12e90639/jnnpsyc00522-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/77f071a42ccf/jnnpsyc00522-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/9ff6a3fe5fe1/jnnpsyc00522-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/ce9d12e90639/jnnpsyc00522-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94bf/488312/77f071a42ccf/jnnpsyc00522-0031-a.jpg

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本文引用的文献

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Prosopagnosia: anatomic basis and behavioral mechanisms.面孔失认症:解剖学基础与行为机制
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Ann Neurol. 1982 Jun;11(6):592-8. doi: 10.1002/ana.410110607.
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Pick's disease. A clinical, computed tomographic, and histologic study with golgi impregnation observations.匹克氏病。一项结合高尔基体浸染观察的临床、计算机断层扫描及组织学研究。
Brain. 2023 Jan 5;146(1):20-41. doi: 10.1093/brain/awac339.
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A clinical-radiological framework of the right temporal variant of frontotemporal dementia.右颞叶额颞痴呆的临床放射学框架。
Brain. 2020 Sep 1;143(9):2831-2843. doi: 10.1093/brain/awaa225.
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Early-stage right temporal lobe variant of frontotemporal dementia: 3 years of follow-up observations.额颞叶痴呆早期右颞叶变异型:3年随访观察
BMJ Case Rep. 2018 Jun 29;2018:bcr-2018-224431. doi: 10.1136/bcr-2018-224431.
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Cortex. 2017 Sep;94:27-38. doi: 10.1016/j.cortex.2017.06.003. Epub 2017 Jun 27.
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