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超重和肥胖成年人的脂肪酸摄入量与血脂谱

[Fatty acids intake and serum lipids profile in overweighted and obese adults].

作者信息

Wolańska Diana, Kłosiewicz-Latoszek Longina

机构信息

Instytut Zywności i Zywienia, Warszawa.

出版信息

Rocz Panstw Zakl Hig. 2012;63(2):155-62.

PMID:22928362
Abstract

BACKGROUND

Many epidemiologic, experimental, and clinical studies have shown that the amounts and type of fat in the diet influence plasma lipid levels. Dietary fat has been shown to have a role in cardiovascular diseases.

OBJECTIVES

The purpose of this study was to describe the relationship between dietary fatty acids and serum lipids in 150 overweight adults.

MATERIAL AND METHODS

The examinations were performed in 150 adults, aged from 25 to 65 years with overweight and obese. Fat intakes are estimated from one 24-hour dietary recall interview. Data obtained with 24-hour questionnaire method were calculated with computer program Dieta 4. Statistical analysis was performed using a computer program Statistica.

RESULTS

Mean energy intake amounted 2579.2 +/- 786.2 kcal per day. The fat intake provided 34.6 +/- 8.5% of total energy, including saturated fatty acid--13.6% of total energy. Saturated fatty acids was not correlated with lipid profiles. Stearic acid was inversely correlated with the high-density lipoprotein. There were no signifificant associations between stearic acid and total cholesterol and plasma LDL cholesterol. Monounsaturated fat, including the oleic acid were affected lipid profiles by decreased total cholesterol and LDL-C. PUFA was correlated with decreased total cholesterol and plasma LDL cholesterol. Inverse correlation between arachidonic acid and HDL-C and between linoleic acid and LDL-C was observed.

CONCLUSIONS

This study indicates that the type of fat, but not only the total amount of fat, predicts serum cholesterol and its fractions levels. The proportion of SFA, MUFA, PUFA in diet determines their effect on serum lipids profile.

摘要

背景

许多流行病学、实验和临床研究表明,饮食中脂肪的数量和类型会影响血脂水平。膳食脂肪已被证明在心血管疾病中起作用。

目的

本研究的目的是描述150名超重成年人膳食脂肪酸与血脂之间的关系。

材料与方法

对150名年龄在25至65岁之间的超重和肥胖成年人进行检查。通过一次24小时饮食回顾访谈估计脂肪摄入量。用计算机程序Dieta 4计算通过24小时问卷调查法获得的数据。使用计算机程序Statistica进行统计分析。

结果

平均能量摄入量为每天2579.2±786.2千卡。脂肪摄入量占总能量的34.6±8.5%,其中饱和脂肪酸占总能量的13.6%。饱和脂肪酸与血脂谱无相关性。硬脂酸与高密度脂蛋白呈负相关。硬脂酸与总胆固醇和血浆低密度脂蛋白胆固醇之间无显著关联。单不饱和脂肪,包括油酸,通过降低总胆固醇和低密度脂蛋白胆固醇影响血脂谱。多不饱和脂肪酸与总胆固醇和血浆低密度脂蛋白胆固醇降低相关。观察到花生四烯酸与高密度脂蛋白胆固醇之间以及亚油酸与低密度脂蛋白胆固醇之间呈负相关。

结论

本研究表明,脂肪的类型而非仅仅脂肪总量可预测血清胆固醇及其各组分水平。饮食中饱和脂肪酸、单不饱和脂肪酸、多不饱和脂肪酸的比例决定了它们对血脂谱的影响。

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