Department of Cardiology, Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey.
Med Sci Monit. 2012 Sep;18(9):CR587-91. doi: 10.12659/msm.883356.
In this study we examined right and left ventricular systolic functions in hepatitis B virus (HBV) patients.
MATERIAL/METHODS: The study included 50 HBsAg-positive patients (mean age; 33±13 years) and 50 other persons (mean age; 28±11 years) as a control group. Transthoracic echocardiography was performed in all the participants. Right and left ventricle systolic parameters were compared between these 2 groups.
In the group of the patients with HBsAg positivity, the right ventricular fractional area change (RV FAC), tricuspid annular plane excursion (TAPSE) and RV myocardial systolic velocity (St) values were lower than in the control group (33±11 vs. 52±13%, p=0.001; 14.6±1.1 vs. 22.2±2.4 mm, p<0.001; 8.6±1.2 vs. 15.8±2.3 cm/s, p<0,001, respectively); the right atrium (RA) and RV diameters were higher than in controls (5.1±1.2 vs. 3.7±0.5 cm, p<0.001; 4.9±0.8 vs. 3.4±0.5 cm p<0.001, respectively); and systolic pulmonary artery pressure was higher than in control (39.3±9.5 vs. 22±8.4 mmHg, p<0.001).
The findings showed that HBV infection may be associated with right ventricular systolic dysfunction and pulmonary hypertension.
本研究旨在探讨乙型肝炎病毒（HBV）感染者的左右心室收缩功能。
材料/方法：本研究纳入了 50 例 HBsAg 阳性患者（平均年龄 33±13 岁）和 50 名作为对照组的其他人员（平均年龄 28±11 岁）。所有参与者均进行了经胸超声心动图检查。比较了两组之间的右心室和左心室收缩参数。
在 HBsAg 阳性组中，右心室分数面积变化（RV FAC）、三尖瓣环平面位移（TAPSE）和 RV 心肌收缩速度（St）值低于对照组（33±11 比 52±13%，p=0.001；14.6±1.1 比 22.2±2.4mm，p<0.001；8.6±1.2 比 15.8±2.3cm/s，p<0.001）；右心房（RA）和 RV 直径大于对照组（5.1±1.2 比 3.7±0.5cm，p<0.001；4.9±0.8 比 3.4±0.5cm，p<0.001）；收缩期肺动脉压高于对照组（39.3±9.5 比 22±8.4mmHg，p<0.001）。
HBV 感染可能与右心室收缩功能障碍和肺动脉高压有关。
