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可卡因与低出生体重风险

Cocaine and the risk of low birth weight.

作者信息

Petitti D B, Coleman C

机构信息

Alameda County Low Birth Weight Study Group, CA.

出版信息

Am J Public Health. 1990 Jan;80(1):25-8. doi: 10.2105/ajph.80.1.25.

Abstract

In a population-based case-control study, we assessed the relation between cocaine use and the risk of low birth weight in Alameda County, California, excluding women who used heroin and/or methadone during pregnancy. After adjustment for confounders, the relative risk of low birth weight in users of cocaine throughout pregnancy was 4.0 (95% CI = 1.8, 8.9). Cocaine use was estimated to account for 10 percent of cases of low birth weight in Black women in Alameda County.

摘要

在一项基于人群的病例对照研究中,我们评估了加利福尼亚州阿拉米达县可卡因使用与低出生体重风险之间的关系,排除了孕期使用海洛因和/或美沙酮的女性。在对混杂因素进行调整后,整个孕期使用可卡因的人群中低出生体重的相对风险为4.0(95%置信区间=1.8,8.9)。据估计,阿拉米达县黑人女性中10%的低出生体重病例可归因于可卡因使用。

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本文引用的文献

1
The teratogenicity of cocaine.
Teratology. 1982 Aug;26(1):17-9. doi: 10.1002/tera.1420260104.
2
Abruptio placentae associated with cocaine use.
Am J Obstet Gynecol. 1983 May 15;146(2):220-1. doi: 10.1016/0002-9378(83)91060-8.
6
Cocaine use during pregnancy: adverse perinatal outcome.孕期使用可卡因:围产期不良结局。
Am J Obstet Gynecol. 1987 Sep;157(3):686-90. doi: 10.1016/s0002-9378(87)80029-7.
7
Medical complications of cocaine abuse.可卡因滥用的医学并发症。
N Engl J Med. 1986 Dec 4;315(23):1495-500. doi: 10.1056/NEJM198612043152327.

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