National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, the Chinese Academy of Sciences, Shanghai 200032, China.
J Integr Plant Biol. 2012 Oct;54(10):703-12. doi: 10.1111/j.1744-7909.2012.01161.x.
Plant secondary metabolites play critical roles in plant-environment interactions. They are synthesized in different organs or tissues at particular developmental stages, and in response to various environmental stimuli, both biotic and abiotic. Accordingly, corresponding genes are regulated at the transcriptional level by multiple transcription factors. Several families of transcription factors have been identified to participate in controlling the biosynthesis and accumulation of secondary metabolites. These regulators integrate internal (often developmental) and external signals, bind to corresponding cis-elements--which are often in the promoter regions--to activate or repress the expression of enzyme-coding genes, and some of them interact with other transcription factors to form a complex. In this review, we summarize recent research in these areas, with an emphasis on newly-identified transcription factors and their functions in metabolism regulation.
植物次生代谢物在植物与环境的相互作用中起着关键作用。它们在不同的器官或组织中，在特定的发育阶段合成，并对生物和非生物的各种环境刺激作出反应。因此，相应的基因在转录水平上受到多个转录因子的调节。已经鉴定出几个转录因子家族参与控制次生代谢物的生物合成和积累。这些调节剂整合内部（通常是发育）和外部信号，与相应的顺式元件（通常位于启动子区域）结合，激活或抑制酶编码基因的表达，其中一些与其他转录因子相互作用形成复合物。在这篇综述中，我们总结了这些领域的最新研究，重点介绍了新鉴定的转录因子及其在代谢调控中的功能。
