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双侧巨大多囊肾，怀疑有恶性病变，囊肿反复出血，伴有急腹症。

Huge bilateral polycystic kidneys with suspicion of malignancy, recurrent bleeding in cysts, and acute abdomen.

作者信息

Bhatty Tan, Moazin Ms, Haque R

机构信息

Division of Urology, Department of Surgical Specialities, King Fahad Medical City, Riyadh, Saudi Arabia.

出版信息

Ecancermedicalscience. 2012;6:267. doi: 10.3332/ecancer.2012.267. Epub 2012 Sep 4.

DOI:10.3332/ecancer.2012.267
PMID:22949929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3430667/
Abstract

UNLABELLED

We present a case of huge bilateral polycystic kidneys, with suspicion of malignancy and repeated admissions with acute abdomen, secondary to bleeding in cysts, and anaemia, requiring affected side nephrectomy.

KEY MESSAGE

Autosomal dominant polycystic kidney disease (ADPKD) mostly ends up with end stage renal disease (ESRD), requiring haemodialysis, with increased risk of malignancy and enlargement of kidneys with its associated complications, mostly dealt with conservatively, except malignancy, which requires nephrectomy.

摘要

未标注

我们报告一例巨大双侧多囊肾病例，怀疑有恶变，因囊肿出血继发急腹症和贫血而反复入院，最终进行了患侧肾切除术。

关键信息

常染色体显性多囊肾病（ADPKD）大多最终发展为终末期肾病（ESRD），需要进行血液透析，恶变风险增加，肾脏增大及其相关并发症大多采用保守治疗，恶变情况除外，恶变需要进行肾切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1e9/3430667/6d89070a6edd/can-6-267fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1e9/3430667/fcc963c8b375/can-6-267fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1e9/3430667/6d89070a6edd/can-6-267fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1e9/3430667/fcc963c8b375/can-6-267fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1e9/3430667/6d89070a6edd/can-6-267fig2.jpg

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本文引用的文献

1
Giant polycystic kidney and acute abdomen in chronic renal failure.慢性肾衰竭中的巨大多囊肾与急腹症
Urol Ann. 2011 Jan;3(1):39-41. doi: 10.4103/0974-7796.75859.
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Prevalence of renal cell carcinoma in patients with autosomal dominant polycystic kidney disease and chronic renal failure.常染色体显性遗传性多囊肾病和慢性肾衰竭患者中肾细胞癌的患病率。
Urology. 2009 Sep;74(3):631-4. doi: 10.1016/j.urology.2009.02.078. Epub 2009 Jul 18.
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Renal cell carcinoma in autosomal dominant polycystic kidney disease.常染色体显性遗传性多囊肾病中的肾细胞癌
Am J Kidney Dis. 2009 Jul;54(1):165-8. doi: 10.1053/j.ajkd.2009.01.270. Epub 2009 May 17.
4
Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study.评估西罗莫司对常染色体显性多囊肾病患者治疗效果的临床概念验证试验：瑞士常染色体显性多囊肾病研究
BMC Nephrol. 2007 Sep 15;8:13. doi: 10.1186/1471-2369-8-13.
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The prevalence of renal cell carcinoma diagnosed at autopsy.尸检诊断的肾细胞癌患病率。
BJU Int. 2005 Jan;95(1):31-3. doi: 10.1111/j.1464-410X.2005.05243.x.
6
Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis.肾移植术前终末期肾病患者肾细胞癌的患病率：一项病理分析。
Kidney Int. 2002 Jun;61(6):2201-9. doi: 10.1046/j.1523-1755.2002.00374.x.
7
Renal contraction therapy for enlarged polycystic kidneys by transcatheter arterial embolization in hemodialysis patients.血液透析患者经导管动脉栓塞术治疗多囊肾增大的肾脏收缩疗法
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