迷迭香酸、鼠尾草酸和迷迭香酸浓度与罗勒（罗勒属）甲醇提取物体外抗氧化和抗菌活性的相关性。

Relevance of carnosic acid, carnosol, and rosmarinic acid concentrations in the in vitro antioxidant and antimicrobial activities of Rosmarinus officinalis (L.) methanolic extracts.

机构信息

Department of Natural Resources, Murcia Institute of Agri-Food Research and Development (IMIDA) , c/Mayor s/n, 30150 La Alberca (Murcia), Spain.

出版信息

J Agric Food Chem. 2012 Sep 26;60(38):9603-8. doi: 10.1021/jf302881t. Epub 2012 Sep 18.

DOI:10.1021/jf302881t

PMID:22957812

Abstract

The importance of the diterpenic and rosmarinic acid content in the biological activities of rosemary extracts has been studied previously, but how the relationship between the concentration of these components affects their antioxidant and antibacterial activities has received little attention. Accordingly, from a total of 150 plants, 27 methanolic extracts were selected, for their similar diterpene contents but different ratios between carnosic acid and carnosol concentrations. In extracts with similar rosmarinic acid contents but differing proportions between carnosic acid and carnosol, the two diterpenes were seen to equally affect the in vitro antioxidant activity; however, and related with the antibacterial efficiency, this biological activity improved when carnosol was the major diterpene component.

摘要

先前已经研究了迷迭香提取物中二萜和迷迭香酸含量在生物活性中的重要性，但这些成分浓度之间的关系如何影响它们的抗氧化和抗菌活性却很少受到关注。因此，从总共 150 种植物中，选择了 27 种甲醇提取物，因为它们具有相似的二萜含量，但 carnosic 酸和 carnosol 浓度之间的比例不同。在迷迭香酸含量相似但 carnosic 酸和 carnosol 之间比例不同的提取物中，这两种二萜同样影响体外抗氧化活性；然而，与抗菌效率相关的是，当 carnosol 是主要二萜成分时，这种生物活性会提高。