• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在常规加热和超声辐射条件下改进的 1,2-二芳基乙醇的合成。

An improved synthesis of 1,2-diarylethanols under conventional heating and ultrasound irradiation.

机构信息

College of Science, Northwest A&F University, Yangling 712100, Shaanxi, China.

出版信息

Molecules. 2012 Sep 7;17(9):10708-15. doi: 10.3390/molecules170910708.

DOI:10.3390/molecules170910708
PMID:22960865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6268955/
Abstract

A simple and efficient synthesis of 1,2-diarylethanols has been developed. The procedure involved the reaction between a variety of toluene derivatives and aryl aldehydes under conventional heating and ultrasound irradiation. This procedure possesses several advantages such as operational simplicity, high yield, safety and environment benignancy. Ultrasound was proved to be very helpful to the reaction, markedly improving the yield and the reaction rate.

摘要

一种简单高效的 1,2-二芳基乙醇的合成方法已经开发出来。该方法涉及在常规加热和超声辐射条件下,各种甲苯衍生物与芳醛之间的反应。该方法具有操作简单、产率高、安全环保等优点。超声对反应有很大的帮助,显著提高了产率和反应速率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd41/6268955/5f0c33a2544c/molecules-17-10708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd41/6268955/5f0c33a2544c/molecules-17-10708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd41/6268955/5f0c33a2544c/molecules-17-10708-g001.jpg

相似文献

1
An improved synthesis of 1,2-diarylethanols under conventional heating and ultrasound irradiation.在常规加热和超声辐射条件下改进的 1,2-二芳基乙醇的合成。
Molecules. 2012 Sep 7;17(9):10708-15. doi: 10.3390/molecules170910708.
2
Efficient and direct synthesis of poly-substituted indeno[1,2-b]quinolines assisted by p-toluene sulfonic acid using high-temperature water and microwave heating via one-pot, three-component reaction.在对甲苯磺酸辅助下,利用高温水和微波加热,通过一锅三组分反应高效直接合成多取代茚并[1,2 - b]喹啉。
Org Biomol Chem. 2006 Nov 7;4(21):3980-5. doi: 10.1039/b611462h. Epub 2006 Sep 29.
3
Improved synthesis of diethyl 2,6-dimethyl-4-aryl-4H-pyran-3,5-dicarboxylate under ultrasound irradiation.超声辐射下二乙基 2,6-二甲基-4-芳基-4H-吡喃-3,5-二羧酸酯的改进合成。
Ultrason Sonochem. 2010 Feb;17(2):367-9. doi: 10.1016/j.ultsonch.2009.09.006. Epub 2009 Sep 26.
4
One-pot three-component Mannich-type reactions using sulfamic acid catalyst under ultrasound irradiation.在超声辐射下使用氨基磺酸催化剂的一锅三组分曼尼希型反应。
Ultrason Sonochem. 2009 Aug;16(6):758-62. doi: 10.1016/j.ultsonch.2009.03.008. Epub 2009 Mar 27.
5
Rapid and efficient synthesis of poly-substituted quinolines assisted by p-toluene sulphonic acid under solvent-free conditions: comparative study of microwave irradiation versus conventional heating.对甲苯磺酸辅助下无溶剂条件下多取代喹啉的快速高效合成:微波辐射与传统加热的对比研究
Org Biomol Chem. 2006 Jan 7;4(1):104-10. doi: 10.1039/b513721g. Epub 2005 Nov 18.
6
Ultrasound assisted efficient conversion of aromatic aldehydes from oximes.超声辅助肟高效转化芳香醛。
Ultrason Sonochem. 2013 Jan;20(1):99-102. doi: 10.1016/j.ultsonch.2012.07.025. Epub 2012 Aug 16.
7
New chiral thiophene-salen chromium complexes for the asymmetric Henry reaction.新型手性噻吩-salen 铬配合物在不对称 Henry 反应中的应用。
J Org Chem. 2009 Mar 6;74(5):2242-5. doi: 10.1021/jo802769y.
8
Poly(4-vinylpyridinium)hydrogen sulfate: a novel and efficient catalyst for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes under conventional heating and ultrasound irradiation.聚(4-乙烯基吡啶)硫酸氢盐:一种新型、高效的催化剂,可在常规加热和超声辐射条件下合成 14-芳基-14H-二苯并[a,j]吖啶。
Ultrason Sonochem. 2012 Jul;19(4):736-9. doi: 10.1016/j.ultsonch.2011.12.004. Epub 2011 Dec 23.
9
Ultrasound-promoted Green Synthesis of pyrido[2,1-a]isoquinoline Derivatives and Studies on their Antioxidant Activity.超声促进的吡啶并[2,1-a]异喹啉衍生物的绿色合成及其抗氧化活性研究。
Comb Chem High Throughput Screen. 2021;24(1):119-128. doi: 10.2174/1386207323666200606212501.
10
Improved synthesis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives catalyzed by urea under ultrasound.超声促进脲催化合成 2,2'-芳基亚甲基双(3-羟基-5,5-二甲基-2-环己烯-1-酮)衍生物
Ultrason Sonochem. 2012 Jan;19(1):1-4. doi: 10.1016/j.ultsonch.2011.05.001. Epub 2011 May 8.

引用本文的文献

1
Synthesis of Cyclic Peptides in SPPS with Npb-OH Photolabile Protecting Group.在 SPPS 中使用 Npb-OH 光解保护基团合成环肽。
Molecules. 2022 Mar 29;27(7):2231. doi: 10.3390/molecules27072231.
2
Ultrasound promoted green synthesis, anticancer evaluation, and molecular docking studies of hydrazines: a pilot trial.超声促进的腙的绿色合成、抗癌评价及分子对接研究:一项初步试验。
J Enzyme Inhib Med Chem. 2022 Dec;37(1):135-144. doi: 10.1080/14756366.2021.1995727.
3
Synthesisand Biological Evaluationof New Substituted Hantzsch Thiazole Derivatives from Environmentally Benign One-Pot Synthesis Using Silica Supported Tungstosilisic Acid as Reusable Catalyst.

本文引用的文献

1
Couplings of benzylic halides mediated by titanocene chloride: synthesis of bibenzyl derivatives.
J Org Chem. 2007 Mar 16;72(6):2251-4. doi: 10.1021/jo062492p. Epub 2007 Feb 20.
2
Sonochemistry and the environment - providing a "green" link between chemistry, physics and engineering.声化学与环境——在化学、物理和工程之间建立“绿色”联系。
Ultrason Sonochem. 2007 Apr;14(4):476-83. doi: 10.1016/j.ultsonch.2006.10.008. Epub 2007 Jan 4.
3
Therapeutic potential of resveratrol: the in vivo evidence.白藜芦醇的治疗潜力:体内证据
以硅胶负载硅钨酸为可重复使用催化剂,通过环境友好的一锅法合成新型取代汉茨希噻唑衍生物及其生物学评价
Molecules. 2017 May 7;22(5):757. doi: 10.3390/molecules22050757.
4
Ultrasound-promoted greener synthesis of novel trifurcate 3-substituted-chroman-2,4-dione derivatives and their drug-likeness evaluation.超声促进新型三叉 3-取代色满-2,4-二酮衍生物的绿色合成及其类药性评价。
Molecules. 2012 Nov 28;17(12):14146-58. doi: 10.3390/molecules171214146.
Nat Rev Drug Discov. 2006 Jun;5(6):493-506. doi: 10.1038/nrd2060. Epub 2006 May 26.
4
Synthesis of oximes under ultrasound irradiation.
Ultrason Sonochem. 2006 Apr;13(3):200-2. doi: 10.1016/j.ultsonch.2005.11.011. Epub 2006 Feb 7.
5
Reduction of arylnitro compounds to azoarenes and/or arylamines by Al/NaOH in methanol under ultrasonic conditions.在超声条件下,通过铝/氢氧化钠在甲醇中将芳基硝基化合物还原为偶氮芳烃和/或芳胺。
Ultrason Sonochem. 2005 Aug;12(6):433-5. doi: 10.1016/j.ultsonch.2004.07.002.
6
Ultrasound-assisted hydrogenation of cinnamaldehyde.
Ultrason Sonochem. 2005 Mar;12(4):319-24. doi: 10.1016/j.ultsonch.2003.12.006.
7
Ultrasound accelerated esterification of bile acids.超声加速胆汁酸的酯化反应。
Ultrason Sonochem. 2004 May;11(3-4):161-5. doi: 10.1016/j.ultsonch.2004.01.013.
8
Combretastatins: from natural products to drug discovery.Combretastatin:从天然产物到药物研发
Nat Prod Rep. 2003 Dec;20(6):558-64. doi: 10.1039/b306797c.
9
Interactions of combretastatin, a new plant-derived antimitotic agent, with tubulin.一种新型植物源抗有丝分裂剂——柯里拉京与微管蛋白的相互作用。
Biochem Pharmacol. 1983 Dec 15;32(24):3864-7. doi: 10.1016/0006-2952(83)90163-6.