Roth A
Hawaii Permanente Medical Group, Honolulu 96816.
Ann Allergy. 1990 Jan;64(1):47-8.
Physicians should suspect ACE inhibitors as the cause of cough in patients whose symptom begins soon after the institution of therapy with this class of drugs. This is particularly important in patients without a personal or family history of atopy, with normal physical findings, chest radiographs, and lung function tests. Rather than subjecting the patient to an extensive workup, substitution of a different antihypertensive agent is an inexpensive way to show whether the ACE inhibitor is the cause of the chronic cough.
对于在开始使用这类药物治疗后不久出现症状的患者，医生应怀疑咳嗽是由血管紧张素转换酶（ACE）抑制剂引起的。这对于没有特应性个人或家族史、体格检查、胸部X光片和肺功能测试均正常的患者尤为重要。与其让患者接受全面检查，换用另一种抗高血压药物是一种成本低廉的方法，可用来确定ACE抑制剂是否为慢性咳嗽的病因。
