评分研究报告 12：评分研究中静脉侧支的发展。
Score Study Report 12: Development of venous collaterals in the Score Study.
机构信息
Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
出版信息
Retina. 2013 Feb;33(2):287-95. doi: 10.1097/IAE.0b013e318263d106.
Abstract
PURPOSE
To investigate the prevalence of venous collaterals after branch and central retinal vein occlusion, assess the association of venous collaterals with other clinical features (including visual acuity), and determine if treatment with intravitreal corticosteroids influences the development of new venous collaterals.
METHODS
Review of data from two multicenter randomized clinical trials in the Standard of Care versus COrticosteroid for REtinal Vein Occlusion (SCORE) Study.
RESULTS
Statistically significant associations of venous collaterals and visual acuity at baseline or at follow-up were not found. Treatment with intravitreal triamcinolone acetonide did not appear to influence the development of venous collaterals.
CONCLUSION
In contrast to some previous reports, development of venous collaterals did not demonstrate an independent association with visual acuity in eyes with branch retinal vein occlusion or central retinal vein occlusion in the SCORE Study. Intravitreal steroid effects do not appear to influence the development of venous collaterals.
摘要
目的
调查分支静脉和中央视网膜静脉阻塞后静脉侧支的发生率，评估静脉侧支与其他临床特征（包括视力）的关系，并确定玻璃体内皮质类固醇治疗是否会影响新静脉侧支的形成。
方法
对标准治疗与皮质类固醇治疗视网膜静脉阻塞的多中心随机临床试验（SCORE 研究）中的数据进行回顾。
结果
未发现静脉侧支和基线或随访时视力之间存在统计学显著关联。玻璃体内曲安奈德治疗似乎并未影响静脉侧支的形成。
结论
与一些先前的报告相反，在 SCORE 研究中，分支视网膜静脉阻塞或中央视网膜静脉阻塞眼的静脉侧支形成与视力之间并未显示出独立的关联。玻璃体内类固醇的作用似乎不会影响静脉侧支的形成。
相似文献
1
Score Study Report 12: Development of venous collaterals in the Score Study.评分研究报告 12：评分研究中静脉侧支的发展。
Retina. 2013 Feb;33(2):287-95. doi: 10.1097/IAE.0b013e318263d106.
2
Prospective study of intravitreal triamcinolone acetonide versus bevacizumab for macular edema secondary to central retinal vein occlusion.前瞻性研究曲安奈德与贝伐单抗治疗视网膜中央静脉阻塞继发黄斑水肿。
Retina. 2011 May;31(5):838-45. doi: 10.1097/IAE.0b013e3181f4420d.
3
Macular sensitivity and morphology after intravitreal injection of triamcinolone acetonide for macular edema with branch retinal vein occlusion.曲安奈德玻璃体腔内注射治疗视网膜静脉分支阻塞伴黄斑水肿后的黄斑敏感性和形态。
Retina. 2012 Oct;32(9):1844-52. doi: 10.1097/IAE.0b013e318259569f.
4
Vitrectomy alone versus vitrectomy with simultaneous intravitreal injection of triamcinolone for macular edema associated with branch retinal vein occlusion.单纯玻璃体切除术与玻璃体切除术联合玻璃体内注射曲安奈德治疗视网膜分支静脉阻塞相关黄斑水肿的对比研究
Ophthalmic Surg Lasers Imaging. 2009 Jan-Feb;40(1):6-12. doi: 10.3928/15428877-20090101-19.
5
Baseline predictors of visual acuity and retinal thickness outcomes in patients with retinal vein occlusion: Standard Care Versus COrticosteroid for REtinal Vein Occlusion Study report 10.视网膜静脉阻塞患者视力和视网膜厚度结果的基线预测因素：视网膜静脉阻塞标准护理与皮质类固醇治疗研究报告10
Ophthalmology. 2011 Feb;118(2):345-52. doi: 10.1016/j.ophtha.2010.06.034.
6
SCORE Study report 1: baseline associations between central retinal thickness and visual acuity in patients with retinal vein occlusion.SCORE研究报告1：视网膜静脉阻塞患者视网膜中央厚度与视力之间的基线关联
Ophthalmology. 2009 Mar;116(3):504-12. doi: 10.1016/j.ophtha.2008.10.017. Epub 2009 Jan 22.
7
Intravitreal triamcinolone acetonide in patients with macular oedema due to branch retinal vein occlusion: a pilot study.玻璃体内注射曲安奈德治疗视网膜分支静脉阻塞所致黄斑水肿的初步研究。
Acta Ophthalmol Scand. 2005 Oct;83(5):600-4. doi: 10.1111/j.1600-0420.2005.00490.x.
8
SD-OCT pattern of retinal venous occlusion with cystoid macular edema treated with Ozurdex®.玻璃体内注射Ozurdex®治疗视网膜静脉阻塞合并黄斑囊样水肿的频域光学相干断层扫描图像特征
Eur J Ophthalmol. 2011 Sep-Oct;21(5):631-6. doi: 10.5301/EJO.2011.7428.
9
Intravitreal triamcinolone acetonide in patients with macular oedema due to central retinal vein occlusion.玻璃体内注射曲安奈德治疗视网膜中央静脉阻塞所致黄斑水肿的患者。
Acta Ophthalmol Scand. 2005 Feb;83(1):71-5. doi: 10.1111/j.1600-0420.2005.00400.x.
10
Collateral vessels on optical coherence tomography angiography in eyes with branch retinal vein occlusion.分支静脉阻塞眼的光相干断层扫描血管造影的侧支血管。
Br J Ophthalmol. 2019 Oct;103(10):1373-1379. doi: 10.1136/bjophthalmol-2018-313322. Epub 2018 Nov 22.
引用本文的文献
1
Ultrawide-Field Optical Coherence Tomography Angiography-Guided Navigated Laser Therapy of Non-Perfused Areas in Branch Retinal Vein Occlusion.超广角光学相干断层扫描血管造影引导下的视网膜分支静脉阻塞无灌注区导航激光治疗
J Clin Med. 2025 Jul 15;14(14):5014. doi: 10.3390/jcm14145014.
2
The influence of different types of collateral vessels on the recurrence of macular edema in branch retinal vein occlusion.不同类型侧支血管对视网膜分支静脉阻塞黄斑水肿复发的影响。
Graefes Arch Clin Exp Ophthalmol. 2025 Jul 21. doi: 10.1007/s00417-025-06911-9.
3
Telangiectatic Capillaries in Retinal Vein Occlusion: Incidence, Topography, and Risk Factors.视网膜静脉阻塞中的毛细血管扩张：发生率、分布部位及危险因素
Ophthalmol Sci. 2025 Feb 27;5(4):100754. doi: 10.1016/j.xops.2025.100754. eCollection 2025 Jul-Aug.
4
Automated interpretation of retinal vein occlusion based on fundus fluorescein angiography images using deep learning: A retrospective, multi-center study.基于深度学习的眼底荧光血管造影图像自动解读视网膜静脉阻塞：一项回顾性多中心研究。
Heliyon. 2024 Jun 19;10(13):e33108. doi: 10.1016/j.heliyon.2024.e33108. eCollection 2024 Jul 15.
5
Optociliary Shunt Vessels or Neovascularisation of the Optic Disc: Fluorescein Angiography Versus Optical Coherence Tomography Angiography.视睫状分流血管或视盘新生血管：荧光素血管造影与光学相干断层扫描血管造影对比
Neuroophthalmology. 2022 Mar 2;46(5):339-342. doi: 10.1080/01658107.2022.2033796. eCollection 2022.
6
The Caliber of Optociliary Shunt Vessels Is Associated with Macular Blood Flow and Visual Acuity in Central Retinal Vein Occlusion.视睫状分流血管管径与视网膜中央静脉阻塞时的黄斑血流及视力相关。
Ophthalmol Sci. 2021 Nov 20;2(1):100083. doi: 10.1016/j.xops.2021.100083. eCollection 2022 Mar.
7
Collateral Vessel Development in Central and Branch Retinal Vein Occlusions Are Associated With Worse Visual and Anatomic Outcomes.中心性和分支性视网膜静脉阻塞的侧支血管发育与更差的视力和解剖学结局相关。
Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):1. doi: 10.1167/iovs.62.14.1.
8
Association between capillary congestion and macular edema recurrence in chronic branch retinal vein occlusion through quantitative analysis of OCT angiography.通过 OCT 血管造影定量分析，探讨毛细血管充血与慢性分支视网膜静脉阻塞黄斑水肿复发的关系。
Sci Rep. 2021 Oct 6;11(1):19886. doi: 10.1038/s41598-021-99429-z.
9
Disease-modifying effects of ranibizumab for central retinal vein occlusion.雷珠单抗治疗视网膜中央静脉阻塞的疾病修饰作用。
Graefes Arch Clin Exp Ophthalmol. 2022 Mar;260(3):799-805. doi: 10.1007/s00417-021-05224-x. Epub 2021 Oct 6.
10
Multimodal Imaging of Microvascular Abnormalities in Retinal Vein Occlusion.视网膜静脉阻塞微血管异常的多模态成像
J Clin Med. 2021 Jan 21;10(3):405. doi: 10.3390/jcm10030405.
本文引用的文献
1
Longer-term outcomes of a prospective study of intravitreal ranibizumab as a treatment for decreased visual acuity secondary to central retinal vein occlusion.一项前瞻性研究的长期结果显示，玻璃体内注射雷珠单抗可有效治疗因视网膜中央静脉阻塞导致的视力下降。
Retina. 2011 May;31(5):821-8. doi: 10.1097/IAE.0b013e3181feccc0.
2
Natural history of visual outcome in central retinal vein occlusion.视网膜中央静脉阻塞的视力预后自然史。
Ophthalmology. 2011 Jan;118(1):119-133.e1-2. doi: 10.1016/j.ophtha.2010.04.019. Epub 2010 Aug 17.
3
A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6.一项比较玻璃体内注射曲安奈德与标准治疗方案治疗视网膜分支静脉阻塞继发黄斑水肿所致视力丧失的疗效和安全性的随机试验：视网膜静脉阻塞的标准治疗与皮质类固醇治疗（SCORE）研究报告6
Arch Ophthalmol. 2009 Sep;127(9):1115-28. doi: 10.1001/archophthalmol.2009.233.
4
A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5.一项比较玻璃体内注射曲安奈德与观察治疗视网膜中央静脉阻塞继发黄斑水肿所致视力丧失的疗效和安全性的随机试验：视网膜静脉阻塞标准治疗与皮质类固醇治疗（SCORE）研究报告5
Arch Ophthalmol. 2009 Sep;127(9):1101-14. doi: 10.1001/archophthalmol.2009.234.
5
SCORE Study report 3: study design and baseline characteristics.SCORE研究报告3：研究设计与基线特征
Ophthalmology. 2009 Sep;116(9):1770-1777.e1. doi: 10.1016/j.ophtha.2009.03.022. Epub 2009 Jul 19.
6
SCORE Study report 1: baseline associations between central retinal thickness and visual acuity in patients with retinal vein occlusion.SCORE研究报告1：视网膜静脉阻塞患者视网膜中央厚度与视力之间的基线关联
Ophthalmology. 2009 Mar;116(3):504-12. doi: 10.1016/j.ophtha.2008.10.017. Epub 2009 Jan 22.
7
Prospective study of intravitreal ranibizumab as a treatment for decreased visual acuity secondary to central retinal vein occlusion.玻璃体内注射雷珠单抗治疗视网膜中央静脉阻塞继发视力下降的前瞻性研究
Am J Ophthalmol. 2009 Feb;147(2):298-306. doi: 10.1016/j.ajo.2008.08.016. Epub 2008 Oct 17.
8
Intravitreal steroids for macular edema: the past, the present, and the future.玻璃体内注射类固醇治疗黄斑水肿：过去、现在与未来。
Surv Ophthalmol. 2008 Mar-Apr;53(2):139-49. doi: 10.1016/j.survophthal.2007.12.005.
9
Early bevacizumab treatment of central retinal vein occlusion.视网膜中央静脉阻塞的早期贝伐单抗治疗。
Am J Ophthalmol. 2007 Dec;144(6):864-71. doi: 10.1016/j.ajo.2007.07.038. Epub 2007 Oct 4.
10
Retinochoroidal collateral veins protect against anterior segment neovascularization after central retinal vein occlusion.视网膜脉络膜侧支静脉可预防视网膜中央静脉阻塞后的眼前段新生血管形成。
Arch Ophthalmol. 2003 Mar;121(3):332-6. doi: 10.1001/archopht.121.3.332.
Zotero 插件