Novotny M, Harvey S, Jemiolo B
Department of Chemistry, Indiana University, Bloomington 47405.
Experientia. 1990 Jan 15;46(1):109-13. doi: 10.1007/BF01955433.
Two terpenic constituents, E,E,-alpha-farnesene and E-beta-farnesene, were found to be elevated in dominant male urine when compared to subordinate or control males. These two urinary compounds were absent in the bladder urine of males; however, they were the most prominent constituents of the perputial gland's aliquots. The results of a two-choice preference test, conducted on ICR/Alb subordinate males, gave a strong indication that these two terpenic constituents introduced into the previously attractive stimulus significantly discouraged prolonged investigations by male mice. The compounds, whether present in the urine matrix or water, rendered the stimulus with a quality behaviorally similar to the urine of dominant males. It appears that they may be synonymous with the previously described aversion signal produced by dominant males. We suggest that these compounds may play a wide-ranging role in the territorial marking behavior of male mice.
与从属雄性或对照雄性相比，发现两种萜类成分，即E,E-α-法尼烯和E-β-法尼烯，在占主导地位的雄性尿液中含量升高。这两种尿液化合物在雄性膀胱尿液中不存在；然而，它们是包皮腺等分试样中最主要的成分。对ICR/Alb从属雄性进行的双选偏好测试结果强烈表明，将这两种萜类成分引入先前有吸引力的刺激物中，会显著抑制雄性小鼠的长时间探究行为。这些化合物，无论存在于尿液基质还是水中，都会使刺激物在行为上具有与占主导地位的雄性尿液相似的性质。看来它们可能与先前描述的占主导地位的雄性产生的厌恶信号同义。我们认为这些化合物可能在雄性小鼠的领地标记行为中发挥广泛作用。
