Burn Center, Red Cross Hospital, Beverwijk, The Netherlands.
Wound Repair Regen. 2012 Sep-Oct;20(5):676-87. doi: 10.1111/j.1524-475X.2012.00820.x.
Long-term outcome of burn scars as well as the relation with clinically relevant parameters has not been studied quantitatively. Therefore, we conducted a detailed analysis on the clinical changes of burn scars in a longitudinal setup. In addition, we focused on the differences in scar quality in relation to the depth, etiology of the burn wound and age of the patient. Burn scars of 474 patients were subjected to a scar assessment protocol 3, 6, and 12 months postburn. Three different age groups were defined (≤5, 5-18, and ≥18 years). The observer part of the patient and observer scar assessment scale revealed a significant (p < 0.001) improvement in scar quality at 12 months compared with the 3- and 6-month data. Predictors for severe scarring are depth of the wound (p < 0.001) and total body surface area burned (p < 0.001). Etiology (p = 0.753) and age (p > 0.230) have no significant influence on scar quality when corrected for sex, total body surface area burned, time, and age or etiology, respectively.
长期的烧伤疤痕结果以及与临床相关参数的关系尚未进行定量研究。因此,我们在纵向研究中对烧伤疤痕的临床变化进行了详细分析。此外,我们还关注了与烧伤深度、病因和患者年龄相关的疤痕质量差异。474 名患者的烧伤疤痕在烧伤后 3、6 和 12 个月接受了疤痕评估方案。定义了三个不同的年龄组(≤5 岁、5-18 岁和≥18 岁)。患者和观察者疤痕评估量表的观察者部分显示,与 3 个月和 6 个月的数据相比,12 个月时疤痕质量有显著改善(p<0.001)。伤口深度(p<0.001)和总体表烧伤面积(p<0.001)是严重疤痕形成的预测因素。病因(p=0.753)和年龄(p>0.230)在分别校正性别、总体表烧伤面积、时间和年龄或病因后,对疤痕质量没有显著影响。