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使用患者和观察者瘢痕评估量表,评估轻度至中度烧伤严重程度患者短期瘢痕质量对最终烧伤瘢痕结局的预测效度。

Predictive validity of short term scar quality on final burn scar outcome using the Patient and Observer Scar Assessment Scale in patients with minor to moderate burn severity.

作者信息

Goei H, van der Vlies C H, Tuinebreijer W E, van Zuijlen P P M, Middelkoop E, van Baar M E

机构信息

Association of Dutch Burn Centres, Burn Centre Maasstad Hospital, Rotterdam, The Netherlands; Department of Plastic, Reconstructive and Hand Surgery, MOVE Research Institute, VU University Medical Centre, Amsterdam, The Netherlands.

Burn Centre, Maasstad Hospital, Rotterdam, The Netherlands.

出版信息

Burns. 2017 Jun;43(4):715-723. doi: 10.1016/j.burns.2016.10.012. Epub 2016 Dec 28.

Abstract

BACKGROUND

The aim of this study was to assess the predictive validity of the Patient and Observer Assessment Scale (POSAS), in order to determine whether it can be used to predict final scar quality.

METHODS

Patients with a maximum TBSA burned of 20% who were treated in a Dutch burn center and participated in two scar assessments at 3 months and >18 months post-burn were included. Scar quality assessment consisted of the POSAS, Dermaspectrometer (color) and Cutometer (elasticity). Predictive validity was determined in three ways: (1) the discriminative ability to distinguish good from reduced long term scar quality, (2) correlations between POSAS items score at the two subsequent assessments and (3) linear regression was conducted to identify POSAS items as independent predictors. Additionally, reliability, construct validity and interpretability were assessed.

RESULTS

A total of 141 patients were included with a mean TBSA burned of 5.2% (±4.5). The ability of the Patient scale to discriminate between good and reduced long term scar quality was adequate with an area under the curve (AUC) of 0.728 (CI 0.640-0.804), the ability of the Observer scale was good with an AUC of 0.854 (CI 0.781-0.911). Correlations between items scored T3 and T>18 were at least adequate. On item level, pain and stiffness (Patient) and pliability and relief (Observer) were identified as significant predictors for reduced long term scar quality. The POSAS was reliable, construct validity was adequate at three months but declined at >18 months.

CONCLUSION

This study found that final scar quality can be adequately predicted by an early POSAS assessment at three months.

摘要

背景

本研究旨在评估患者和观察者评估量表(POSAS)的预测效度,以确定其是否可用于预测最终瘢痕质量。

方法

纳入在荷兰一家烧伤中心接受治疗、烧伤总面积最大为20%且在烧伤后3个月和超过18个月时参与两次瘢痕评估的患者。瘢痕质量评估包括POSAS、皮肤光谱仪(颜色)和皮肤弹性测定仪(弹性)。通过三种方式确定预测效度:(1)区分长期瘢痕质量良好与降低的鉴别能力;(2)两次后续评估中POSAS项目得分之间的相关性;(3)进行线性回归以确定POSAS项目作为独立预测因素。此外,还评估了信度、结构效度和可解释性。

结果

共纳入141例患者,平均烧伤总面积为5.2%(±4.5)。患者量表区分长期瘢痕质量良好与降低的能力足够,曲线下面积(AUC)为0.728(95%CI 0.640 - 0.804),观察者量表的能力良好,AUC为0.854(95%CI 0.781 - 0.911)。T3和T>18时项目得分之间的相关性至少足够。在项目层面,疼痛和僵硬(患者)以及柔韧性和缓解情况(观察者)被确定为长期瘢痕质量降低的显著预测因素。POSAS具有可靠性,三个月时结构效度足够,但在超过18个月时下降。

结论

本研究发现,在三个月时通过早期POSAS评估可以充分预测最终瘢痕质量。

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