马来西亚发现的新型 HIV-1 CRF53_01B 的基因组序列。
Genome sequences of a novel HIV-1 CRF53_01B identified in Malaysia.
机构信息
Centre of Excellence for Research in AIDS, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
出版信息
J Virol. 2012 Oct;86(20):11398-9. doi: 10.1128/JVI.01932-12.
Abstract
A novel HIV-1 genotype designated CRF53_01B was recently characterized from three epidemiologically unrelated persons in Malaysia. Here we announced three recently isolated full-length genomes of CRF53_01B, which is likely to be phylogenetically linked to CRF33_01B, circulating widely in Southeast Asia. The genome sequences may contribute to HIV-1 molecular surveillance and future vaccine development in the region.
摘要
一种新型 HIV-1 基因型被命名为 CRF53_01B，最近在马来西亚的三个无关联的个体中被发现。在此，我们报道了三种最近分离到的 CRF53_01B 全长基因组，该基因型可能与广泛流行于东南亚的 CRF33_01B 存在系统进化上的联系。该基因组序列可能有助于该地区的 HIV-1 分子监测和未来的疫苗研发。
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