Australian School of Advanced Medicine, Macquarie University, Sydney, NSW, Australia.
Ophthalmologica. 2012;228(4):214-21. doi: 10.1159/000342157. Epub 2012 Sep 19.
The ocular circulation provides readily visible information about the state of the systemic circulation, as well as being potentially of relevance to the pathogenesis of ocular disorders such as glaucoma. The interaction between intraocular pressure, retinal vessels and cerebrospinal fluid pressure located at the retrolaminar portion of the eye has been of great interest for both ophthalmic and neurological clinicians and researchers. Understanding the relationship between these physiological parameters can explain phenomena such as spontaneous retinal venous pulsatility, and characterize the effects of the translaminar pressure gradient. It may be feasible to use measurable changes in venous pulsatility to enhance clinical assessment in different diseases. In this article we review recent findings on ocular hemodynamics and the relevance of these parameters in the diagnosis of ophthalmic and neurological diseases.
眼循环提供了关于全身循环状态的易于观察的信息,并且可能与青光眼等眼部疾病的发病机制有关。眼内压、视网膜血管以及位于眼后段的脑脊液压力之间的相互作用一直是眼科和神经科临床医生和研究人员非常感兴趣的话题。了解这些生理参数之间的关系可以解释自发性视网膜静脉搏动等现象,并描述跨层压力梯度的影响。利用静脉搏动的可测量变化来增强不同疾病的临床评估可能是可行的。本文综述了眼血流动力学的最新发现及其在眼科和神经疾病诊断中的相关性。