Verma Rajesh, Lalla Rakesh, Patil Tushar B
Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2012 Sep 25;2012:bcr2012006845. doi: 10.1136/bcr-2012-006845.
Varicella zoster virus (VZV)-induced vasculopathy is an uncommon cause of stroke in a young immunocompetent host. Owing to scarcity of data of VZV-induced vasculopathy and lack of awareness about this condition and its diagnostic test, these cases may be easily missed. In this case, we report an immunocompetent host presenting right-side hemiplegia with motor aphasia and complete loss of vision in the left eye due to complete occlusion of the left common carotid artery without any history of skin rash preceding stroke. Cerebrospinal fluid analysis for varicella antibody revealed very high titres and CT aortogram demonstrated aortoarteritis with occlusion of left common carotid artery. To our knowledge, varicella zoster vasculopathy-associated aortoarteritis has not been described in the literature.
水痘带状疱疹病毒(VZV)诱发的血管病是年轻免疫功能正常宿主中导致中风的罕见原因。由于VZV诱发的血管病数据稀缺,且对这种病症及其诊断测试缺乏认识,这些病例可能很容易被漏诊。在此病例中,我们报告了一名免疫功能正常的宿主,因左侧颈总动脉完全闭塞出现右侧偏瘫、运动性失语和左眼完全失明,中风前无任何皮疹病史。水痘抗体的脑脊液分析显示滴度非常高,CT主动脉造影显示主动脉动脉炎伴左侧颈总动脉闭塞。据我们所知,文献中尚未描述水痘带状疱疹血管病相关的主动脉动脉炎。