Geiser M H, Diermann U, Riva C E
J Biomed Opt. 1999 Oct;4(4):459-64. doi: 10.1117/1.429960.
A compact instrument is described that allows the measurement of the laser Doppler flow parameters, i.e., the velocity, the volume, and flow of blood in the foveal region of the human choroidal vascular system. This new device uses the optical principle of confocality for the delivery of the laser light to the site of measurement and heterodyne detection of the Doppler frequency shifted scattered light. Power of the incident light (785 nm) at the cornea is 90 μW. Measurements were obtained in both eyes of a group of 21 normal volunteers without pupil dilatation. We determined the intrasubject reproducibility and the minimum statistically significant detectable changes in the flow parameters for a group of 21 eyes (one in each subject). Linear correlations were also established between the flow parameters in the right and left eyes. © 1999 Society of Photo-Optical Instrumentation Engineers.
描述了一种紧凑型仪器,它能够测量激光多普勒血流参数,即人脉络膜血管系统中央凹区域的血流速度、血流量和血流。这种新设备利用共焦光学原理将激光传输到测量部位,并对多普勒频移散射光进行外差检测。角膜处入射光(785纳米)的功率为90微瓦。在21名未散瞳的正常志愿者的双眼上进行了测量。我们确定了一组21只眼睛(每个受试者一只眼睛)的受试者内重复性以及血流参数中最小的统计学显著可检测变化。还建立了左右眼血流参数之间的线性相关性。©1999年美国光学仪器工程师协会。