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本文引用的文献

1
Etiology and treatment of hypogonadism in adolescents.青少年性腺功能减退症的病因和治疗。
Pediatr Clin North Am. 2011 Oct;58(5):1181-200, x. doi: 10.1016/j.pcl.2011.07.009.
2
Influence of sports participation on bone health in the young athlete: a review of the literature.运动参与对年轻运动员骨骼健康的影响:文献综述。
PM R. 2011 Sep;3(9):861-7. doi: 10.1016/j.pmrj.2011.05.019.
3
Bone microarchitecture is impaired in adolescent amenorrheic athletes compared with eumenorrheic athletes and nonathletic controls.与月经正常的运动员和非运动员对照组相比,青春期闭经运动员的骨微结构受损。
J Clin Endocrinol Metab. 2011 Oct;96(10):3123-33. doi: 10.1210/jc.2011-1614. Epub 2011 Aug 3.
4
Mortality rates in patients with anorexia nervosa and other eating disorders. A meta-analysis of 36 studies.神经性厌食症及其他饮食失调患者的死亡率。36项研究的荟萃分析。
Arch Gen Psychiatry. 2011 Jul;68(7):724-31. doi: 10.1001/archgenpsychiatry.2011.74.
5
The utility of the gonadotrophin releasing hormone (GnRH) test in the diagnosis of polycystic ovary syndrome (PCOS).促性腺激素释放激素(GnRH)试验在多囊卵巢综合征(PCOS)诊断中的应用。
Endokrynol Pol. 2011;62(2):120-8.
6
Leptin is an effective treatment for hypothalamic amenorrhea.瘦素是治疗下丘脑性闭经的有效方法。
Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6585-90. doi: 10.1073/pnas.1015674108. Epub 2011 Apr 4.
7
Effect of fitness and physical activity on bone mass in adolescents: the HELENA Study.健身和体育活动对青少年骨量的影响:HELENA 研究。
Eur J Appl Physiol. 2011 Nov;111(11):2671-80. doi: 10.1007/s00421-011-1897-0. Epub 2011 Mar 11.
8
Emerging therapeutic opportunities for skeletal restoration.骨骼修复的新兴治疗机会。
Nat Rev Drug Discov. 2011 Feb;10(2):141-56. doi: 10.1038/nrd3299.
9
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know.医学研究所 2011 年关于钙和维生素 D 的膳食参考摄入量报告:临床医生需要了解的内容。
J Clin Endocrinol Metab. 2011 Jan;96(1):53-8. doi: 10.1210/jc.2010-2704. Epub 2010 Nov 29.
10
Body mass, training, menses, and bone in adolescent runners: a 3-yr follow-up.青少年跑者的体重、训练、月经和骨骼:一项 3 年随访研究。
Med Sci Sports Exerc. 2011 Jun;43(6):959-66. doi: 10.1249/MSS.0b013e318201d7bb.

女性运动员三联征。

The female athlete triad.

机构信息

Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.

出版信息

Sports Health. 2012 Jul;4(4):302-11. doi: 10.1177/1941738112439685.

DOI:10.1177/1941738112439685
PMID:23016101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3435916/
Abstract

CONTEXT

The female athlete triad (the triad) is an interrelationship of menstrual dysfunction, low energy availability (with or without an eating disorder), and decreased bone mineral density; it is relatively common among young women participating in sports. Diagnosis and treatment of this potentially serious condition is complicated and often requires an interdisciplinary team.

EVIDENCE ACQUISITION

Articles from 1981 to present found on PubMed were selected for review of major components of the female athlete triad as well as strategies for diagnosis and treatment of the conditions.

RESULTS

The main goal in treatment of young female athletes with the triad is a natural return of menses as well as enhancement of bone mineral density. While no specific drug intervention has been shown to consistently improve bone mineral density in this patient population, maximizing energy availability and optimizing vitamin D and calcium intake are recommended.

CONCLUSIONS

Treatment requires a multidisciplinary approach involving health care professionals as well as coaches and family members. Prevention of this condition is important to minimize complications of the female athlete triad.

摘要

背景

女性运动员三联征(三联征)是一种月经功能障碍、能量供应不足(伴有或不伴有饮食失调)和骨密度降低的相互关系;它在参与运动的年轻女性中较为常见。这种潜在严重疾病的诊断和治疗很复杂,通常需要多学科团队。

证据获取

从 1981 年至今,从 PubMed 上选择了文章,以回顾女性运动员三联征的主要组成部分以及诊断和治疗这些疾病的策略。

结果

治疗年轻女性运动员三联征的主要目标是自然恢复月经,以及提高骨密度。虽然没有特定的药物干预措施被证明能持续改善该患者群体的骨密度,但建议最大限度地提高能量供应,并优化维生素 D 和钙的摄入。

结论

治疗需要多学科的方法,涉及医疗保健专业人员以及教练和家庭成员。预防这种情况对于减少女性运动员三联征的并发症很重要。