Pollock I, Warner J O
Heart and Lung Institute, Brompton Hospital, London.
Arch Dis Child. 1990 Jan;65(1):74-7. doi: 10.1136/adc.65.1.74.
We performed an objective evaluation of 39 children whose behaviour was observed by their parents to improve on an artificial food additive free diet and to deteriorate with dietary lapses. Only 19 children completed a double blind placebo controlled challenge study with artificial food colours. In these children food colours were shown to have an adverse effect on a daily Conners' rating of behaviour, but most parents could not detect these changes. A pharmacological mechanism of food additive intolerance is proposed to explain these effects.
我们对39名儿童进行了客观评估,这些儿童的父母观察到他们在食用不含人工食品添加剂的饮食时行为有所改善,而饮食出现差错时行为则会恶化。只有19名儿童完成了一项针对人工食用色素的双盲安慰剂对照激发试验研究。在这些儿童中,食用色素被证明会对每日的康纳斯行为评定产生不良影响,但大多数家长并未察觉到这些变化。我们提出了一种食物添加剂不耐受的药理机制来解释这些影响。