Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Appl Environ Microbiol. 2012 Dec;78(23):8488-91. doi: 10.1128/AEM.02258-12. Epub 2012 Sep 28.
In turkey-derived Campylobacter coli isolates of a unique lineage (cluster II), the tetracycline resistance determinant tet(O) was chromosomal and was part of a gene cassette (transposon) interrupting a Campylobacter jejuni-associated putative citrate transporter gene. In contrast, the swine-derived C. coli strain 6461 harbored a chromosomal tet(O) in a different genomic location.
在独特谱系(II 群)的来源于火鸡的弯曲杆菌属大肠杆菌分离株中,四环素耐药决定簇 tet(O)位于染色体上,是一个基因盒(转座子)的一部分,该基因盒中断了与空肠弯曲杆菌相关的假定柠檬酸转运蛋白基因。相比之下,来源于猪的弯曲杆菌属大肠杆菌菌株 6461 则在不同的基因组位置拥有一个染色体 tet(O)。