Goto M, Ebihara S
Department of Animal Physiology, Faculty of Agriculture, Nagoya University, Japan.
Neurosci Lett. 1990 Jan 22;108(3):267-72. doi: 10.1016/0304-3940(90)90652-p.
The sensitivity of light-induced suppression of pineal melatonin content was compared between C3H mice with hereditary retinal degeneration and CBA mice with normal retinas. At 2 h before lights on of light-dark (LD) cycles, when pineal melatonin content is the highest in both strains, groups of mice were exposed to different intensities of white fluorescent light (100, 0.14, 0.017 lux in both strains and 0.0021 and 0.00026 lux in CBA mice). For each intensity, pineals were collected just before and 5, 15 and 30 min after exposure to light. In C3H mice, the threshold of light intensity to suppress pineal melatonin content was between 0.14 and 0.017 lux, whereas that in CBA mice was between 0.0021 and 0.00026 lux. These results suggest that both rods and cones mediate photic information to the pineal gland in mice.
比较了遗传性视网膜变性的C3H小鼠和视网膜正常的CBA小鼠对光诱导的松果体褪黑素含量抑制的敏感性。在明暗（LD）循环开灯前2小时，此时两种品系小鼠的松果体褪黑素含量均最高，将小鼠分组暴露于不同强度的白色荧光下（两种品系均为100、0.14、0.017勒克斯，CBA小鼠为0.0021和0.00026勒克斯）。对于每种强度，在暴露于光之前以及暴露后5、15和30分钟采集松果体。在C3H小鼠中，抑制松果体褪黑素含量的光强度阈值在0.14至0.017勒克斯之间，而在CBA小鼠中，该阈值在0.0021至0.00026勒克斯之间。这些结果表明，视杆细胞和视锥细胞都将光信息传递至小鼠的松果体。
