在 DNA 折纸支架上组装异质功能纳米材料。
Assembly of heterogeneous functional nanomaterials on DNA origami scaffolds.
机构信息
Department of Applied Physics & Applied Mathematics, Columbia University, New York, NY 10027, USA.
出版信息
Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11325-7. doi: 10.1002/anie.201206389. Epub 2012 Oct 10.
Abstract
One on each side: gold nanoparticles (AuNPs) and semiconducting quantum dots (QDs) are integrated on a single DNA origami scaffold. Streptavidin-functionalized QDs bind to biotin anchors on one side of the DNA origami, while DNA-coated AuNPs bind through DNA hybridization to single-stranded DNA on the other side of the scaffold. This approach offers a new path toward the organization of complex systems consisting of disparate materials.
摘要
一侧一个
金纳米粒子 (AuNPs) 和半导体量子点 (QDs) 被整合在单个 DNA 折纸支架上。链霉亲和素功能化的 QDs 与 DNA 折纸一侧的生物素锚结合，而 DNA 包裹的 AuNPs 通过 DNA 杂交与支架另一侧的单链 DNA 结合。这种方法为组织由不同材料组成的复杂系统提供了一条新途径。
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