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生长抑素类似物(SMS 201-995)可抑制大鼠肾上腺对基础状态及血管紧张素II刺激的3H-胸腺嘧啶核苷的摄取。

Somatostatin analog (SMS 201-995) inhibits the basal and angiotensin II-stimulated 3H-thymidine uptake by rat adrenal glands.

作者信息

Pawlikowski M, Lewiński A, Sewerynek E, Szkudliński M, Kunert-Radek J, Wajs E

机构信息

Institute of Endocrinology, Medical Academy of Lódź, Poland.

出版信息

Biochem Biophys Res Commun. 1990 Feb 14;166(3):1171-5. doi: 10.1016/0006-291x(90)90989-z.

DOI:10.1016/0006-291x(90)90989-z
PMID:2306237
Abstract

The effects of a long-acting somatostatin analog SMS 201-995 injections on the basal and angiotensin II-stimulated [3H]-thymidine uptake by the rat adrenal glands incubated in vitro were examined. It was shown that SMS 201-995 significantly inhibited the [3H]-thymidine uptake and, additionally, suppressed the stimulatory effect of a single angiotensin II injection.

摘要

研究了长效生长抑素类似物SMS 201-995注射对体外培养的大鼠肾上腺基础和血管紧张素II刺激的[3H]-胸腺嘧啶核苷摄取的影响。结果表明,SMS 201-995显著抑制[3H]-胸腺嘧啶核苷摄取,此外,还抑制单次注射血管紧张素II的刺激作用。

相似文献

1
Somatostatin analog (SMS 201-995) inhibits the basal and angiotensin II-stimulated 3H-thymidine uptake by rat adrenal glands.生长抑素类似物(SMS 201-995)可抑制大鼠肾上腺对基础状态及血管紧张素II刺激的3H-胸腺嘧啶核苷的摄取。
Biochem Biophys Res Commun. 1990 Feb 14;166(3):1171-5. doi: 10.1016/0006-291x(90)90989-z.
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Inhibitory effect of somatostatin on the basal and TSH-stimulated 3H-thymidine incorporation into rat thyroid lobes incubated in vitro.生长抑素对体外培养的大鼠甲状腺叶基础状态及促甲状腺激素刺激下的³H-胸腺嘧啶核苷掺入的抑制作用。
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