生长抑素类似物（SMS 201-995）可抑制大鼠肾上腺对基础状态及血管紧张素II刺激的3H-胸腺嘧啶核苷的摄取。
Somatostatin analog (SMS 201-995) inhibits the basal and angiotensin II-stimulated 3H-thymidine uptake by rat adrenal glands.
作者信息
Pawlikowski M, Lewiński A, Sewerynek E, Szkudliński M, Kunert-Radek J, Wajs E
机构信息
Institute of Endocrinology, Medical Academy of Lódź, Poland.
出版信息
Biochem Biophys Res Commun. 1990 Feb 14;166(3):1171-5. doi: 10.1016/0006-291x(90)90989-z.
PMID:2306237
Abstract
The effects of a long-acting somatostatin analog SMS 201-995 injections on the basal and angiotensin II-stimulated [3H]-thymidine uptake by the rat adrenal glands incubated in vitro were examined. It was shown that SMS 201-995 significantly inhibited the [3H]-thymidine uptake and, additionally, suppressed the stimulatory effect of a single angiotensin II injection.
摘要
研究了长效生长抑素类似物SMS 201-995注射对体外培养的大鼠肾上腺基础和血管紧张素II刺激的[3H]-胸腺嘧啶核苷摄取的影响。结果表明，SMS 201-995显著抑制[3H]-胸腺嘧啶核苷摄取，此外，还抑制单次注射血管紧张素II的刺激作用。
Zotero 插件